CC BY-NC-ND 4.0 · Thorac Cardiovasc Surg Rep 2023; 12(01): e14-e16
DOI: 10.1055/s-0043-1762551
Case Report: Thoracic

First Ultrasound-Assisted Thrombolysis for Pulmonary Embolism after Lung Surgery

Koen Selten
1   Department of Thoracic Surgery, Faculty of Medicine, RWTH Aachen University, Aachen, Nordrhein-Westfalen, Germany
1   Department of Thoracic Surgery, Faculty of Medicine, RWTH Aachen University, Aachen, Nordrhein-Westfalen, Germany
Alexander Kersten
2   Department of Cardiology, Angiology, and Intensive Care, Faculty of Medicine, RWTH University Hospital, Aachen, Germany
Sebastian Kalverkamp
1   Department of Thoracic Surgery, Faculty of Medicine, RWTH Aachen University, Aachen, Nordrhein-Westfalen, Germany
› Author Affiliations


Background Experience with early postoperative catheter-directed ultrasound-assisted thrombolysis (USAT) in high-risk pulmonary embolism (PE) is limited. A first case of USAT directly after pulmonary surgery is presented.

Case Description A 60-year-old female patient with two malignancies (triple negative breast cancer and pulmonary squamous cell carcinoma) underwent video-assisted lobectomy. The second postoperative day, she developed PE with hemodynamic deterioration. Note that 24 mg of alteplase was applied by USAT. After 3 days she was successfully weaned from ventilation and vasopressors.

Conclusion USAT for acute PE is possible after major pulmonary resections and seems promising if reperfusion is needed.

Authors' Contribution

AK and SK were directly involved in treatment of this clinical case, KS and KD obtained patient data, KS and KD wrote the first version of the manuscript, all authors critically revised the manuscript.


This case report study was approved by the independent medical ethics committee and written informed consent was obtained by the patient.

Publication History

Received: 17 October 2022

Accepted: 03 December 2022

Article published online:
06 March 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (

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