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CC BY-NC-ND 4.0 · Revista Chilena de Ortopedia y Traumatología 2023; 64(01): e50-e57
DOI: 10.1055/s-0043-1760860
Artículo de Revisión | Review Article

Hipoxia e hipersensibilidad de tipo IV: patogenia dual en reacciones a implantes de cadera

Article in several languages: español | English
Mauricio Quezada
1   Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile
,
Felipe Eltit 
2   Vancouver Prostate Centre, Vancouver, Canada
3   Facultad de Ingeniería Biomédica, University of British Columbia, Vancouver, Canada
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Resumen

Antecedentes Las reacciones tisulares adversas (RTAs) a implantes de cadera afectan a una alta proporción de pacientes. Si bien fueron inicialmente descritas en articulaciones de metal sobre metal, un creciente número de estudios señala su presencia en otros tipos de implante. El gran número de pacientes con prótesis de cadera en el mundo señala la urgencia de comprender cabalmente los mecanismos que dan origen a RTAs para el desarrollo de alternativas de monitoreo, diagnóstico y terapéuticas eficientes.

Ámbito de revisión y público objetivo En la siguiente revisión bibliográfica, abarcamos desde la corrosión y el desgaste de los materiales utilizados en implantes de cadera hasta los mecanismos celulares e inmunológicos involucrados, con el fin de ofrecer una visión actualizada de antecedentes clínicos y científicos a estudiantes, cirujanos ortopédicos e investigadores.

Palabras Clave

pseudotumores - sinovia - cromo y cobalto - implantes ortopédicos - artroplastía de cadera - corrosión de implantes


Publication History

Received: 04 February 2020

Accepted: 28 September 2022

Article published online:
18 May 2023

© 2023. Sociedad Chilena de Ortopedia y Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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