Planta Med 2018; 84(09/10): 704-709
DOI: 10.1055/s-0043-122747
Natural Product Chemistry and Analytical Studies
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

Prenylated Flavonoids and Phenolic Compounds from the Rhizomes of Marine Phanerogam Cymodocea nodosa

Abla Smadi
1   Université de Batna 1, Faculté des Sciences de la matière, Département de Chimie, Laboratoire de Chimie et Chimie de lʼEnvironnement (LCCE), Batna, Algérie
,
Maria Letizia Ciavatta
2   Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Pozzuoli (Na), Italy
,
Fatma Bitam
3   Université de Batna 2, Faculté de Médecine, Département de Pharmacie, Batna, Algérie
,
Marianna Carbone
2   Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Pozzuoli (Na), Italy
,
Guido Villani
2   Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Pozzuoli (Na), Italy
,
Margherita Gavagnin
2   Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Pozzuoli (Na), Italy
› Author Affiliations
Further Information

Publication History

received 07 August 2017
revised 03 November 2017

accepted 08 November 2017

Publication Date:
23 November 2017 (online)

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Abstract

Chemical investigation of the rhizomes of the marine phanerogam Cymodocea nodosa resulted in the isolation of two new prenylated flavon-di-O-glycosides, cymodioside A (1) and B (2), along with known phenolic compounds 3–7, some of which never reported from seagrasses to date. The structures of compounds 1 and 2 were established by extensive nuclear magnetic resonance analysis. In addition, the absolute configuration of 4-(2,5-dihydroxyhexyl) benzene-1,2-diol (7), which was not previously reported in the literature, has been now determined.

Key words

seagrass - Cymodocea nodosa - Cymodoceaceae - prenylflavonoids - NMR

Supporting Information

    The 1D and 2D of cymodioside A (1) and B (2), compound 7 and its MPA esters 7a–7b, compound 8, and MTPA esters 8a–8b are available as Supporting Information.

  • Supporting Information
 

  • References

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