Salvage-Chirurgie bei Tumorrezidiven der Mundhöhle – Einfluss der vorherigen Behandlung und des Patientenalters

Tam S et al. Estimating Survival After Salvage Surgery for Recurrent Oral Cavity Cancer. JAMA Otolaryngol Head Neck Surg 2017; 143:685–690

Loko-regionäre Rezidive eines Plattenepithelkarzinoms der Mundhöhle sind lebensbedrohlich und eine klinische Herausforderung. Welche Rolle spielt in diesen Fällen die Salvage-Chirurgie?

• Literatur

• 1 Rose BS. et al. Population-based study of competing mortality in head and neck cancer. J Clin Oncol 2011; 29: 3503-3509 doi:10.1200/JCO.2011.35.7301
• 2 Massa ST. et al. Competing causes of death in the head and neck cancer population. Oral Oncol 2017; 65: 8-15 doi:10.1016/j.oraloncology.2016.12.006
• 3 Bernier J. et al. Defining risk levels in locally advanced head and neck cancers: a comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (#9501). Head Neck 2005; 27: 843-850 doi:10.1002/hed.20279
• 4 Tan HK. et al. Salvage surgery after concomitant chemoradiation in head and neck squamous cell carcinomas – stratification for postsalvage survival. Head Neck 2010; 32: 139-147 doi:10.1002/hed.21159
• 5 Harrell FE. et al. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat Med 1996; 15: 361-387 doi:10.1002/(SICI)1097–0258(19960229)15:4<361::AID-SIM168>3.0.CO;2–4