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CC BY-NC-ND 4.0 · Laryngorhinootologie 2018; 97(S 01): S3-S47
DOI: 10.1055/s-0043-121594
DOI: 10.1055/s-0043-121594
Referat
Immuntherapie – Die neue Ära in der Onkologie
Artikel in mehreren Sprachen: deutsch | EnglishWeitere Informationen
Publikationsverlauf
Publikationsdatum:
22. März 2018 (online)
Zusammenfassung
In den letzten Jahren wurden bedeutende Fortschritte auf dem Gebiet der Immuntherapie erreicht mit teils langanhaltendem Therapieansprechen bei unterschiedlichsten Tumorentitäten. Die Basis hierfür bildet ein verbessertes Verständnis der Interaktion zwischen Tumor und Immunsystem und der damit verbundenen Integration immuntherapeutischer Ansätze in die klinische Routine. Die hierbei eingesetzten immuntherapeutischen Strategien greifen auf unterschiedlichen Ebenen der Immunantwort ein, fördern direkt oder indirekt die Zerstörung der Tumorzellen durch die körpereigene Abwehr und reichen von Zytokintherapien über Vakzinierungen und den Einsatz onkolytischer Viren bis hin zu monoklonalen Antikörpertherapien und dem adoptiven Zelltransfer.
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