CC BY-NC-ND 4.0 · Endosc Int Open 2017; 05(11): E1076-E1080
DOI: 10.1055/s-0043-117951
Case report
Eigentümer und Copyright ©Georg Thieme Verlag KG 2017

Slow-growing amelanotic malignant melanoma of the esophagus with long survival: a case report and review of the literature

Yutaka Hirayama
1   Department of Endoscopy, Aichi Cancer Center Hospital, Aichi, Japan
,
Tajika Masahiro
1   Department of Endoscopy, Aichi Cancer Center Hospital, Aichi, Japan
,
Tsutomu Tanaka
1   Department of Endoscopy, Aichi Cancer Center Hospital, Aichi, Japan
,
Makoto Ishihara
1   Department of Endoscopy, Aichi Cancer Center Hospital, Aichi, Japan
,
Sachiyo Ohnishi
1   Department of Endoscopy, Aichi Cancer Center Hospital, Aichi, Japan
,
Kazuo Hara
2   Department of Gastroenterology, Aichi Cancer Center Hospital, Aichi, Japan
,
Nobumasa Mizuno
2   Department of Gastroenterology, Aichi Cancer Center Hospital, Aichi, Japan
,
Susumu Hijioka
2   Department of Gastroenterology, Aichi Cancer Center Hospital, Aichi, Japan
,
Nozomi Okuno
2   Department of Gastroenterology, Aichi Cancer Center Hospital, Aichi, Japan
,
Tetsuya Abe
3   Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, Japan
,
Norihisa Uemura
3   Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, Japan
,
Jiro Kawakami
3   Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, Japan
,
Shintarou Kurahashi
3   Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, Japan
,
Yasuhiro Shimizu
3   Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, Japan
,
Yasushi Yatabe
4   Department of Pathology and Molecular Diagnosis, Aichi Cancer Center Hospital, Aichi, Japan
,
Yasumasa Niwa
1   Department of Endoscopy, Aichi Cancer Center Hospital, Aichi, Japan
› Author Affiliations
Further Information

Publication History

submitted 08 March 2017

accepted after revision 26 June 2017

Publication Date:
27 October 2017 (online)

Abstract

Background and study aims We report a case of amelanotic malignant melanoma of the esophagus (AMME), an exceedingly rare disease. A 77-year-old Japanese woman presented to our hospital with features suggestive of a middle esophageal submucosal tumor, which was diagnosed pathologically as AMME. The patient underwent thoracoscopic resection of the esophagus and laparoscopic gastric tube reconstruction. Three years after surgery, computed tomography showed no recurrence. Generally, the prognosis of malignant melanoma of the esophagus is very poor. However, our patient had no recurrence, and is alive 3 years after surgery and 5 years after the tumor was first detected.

 
  • References

  • 1 Taniyama K, Suzuki H, Sakuramachi S. et al. Amelanotic malignant melanoma of the esophagus: case report and review of the literature. Jpn J Clin Oncol 1990; 20: 286-295
  • 2 Stringa O, Valdez R, Beguerie JR. et al. Primary amelanotic melanoma of the esophagus. Int J Dermatol 2006; 45: 1207-1210 Review
  • 3 Kranzfelder M, Seidl S, Dobritz M. et al. Amelanotic esophageal malignant melanoma: case report and short review of the literature. Case Rep Gastroenterol 2008; 2: 224-231
  • 4 Ramaswamy B, Bhandarkar AM, Venkitachalam S. et al. Amelanotic malignant melanoma of the cervical oesophagus. BMJ Case Rep 2014; 2014
  • 5 Naomoto Y, Perdomo JA, Kamikawa Y. et al. Primary malignant melanoma of the esophagus: report of a case successfully treated with pre- and post-operative adjuvant hormone-chemotherapy. Jpn J Clin Oncol 1998; 28: 758-761
  • 6 Yano M, Shiozaki H, Murata A. et al. Primary malignant melanoma of the esophagus associated with adenocarcinoma of the lung. Surg Today 1998; 28: 405-408
  • 7 Kato N, Kamino K, Yamashita T. et al. Primary malignant melanoma of the esophagus. Gan No Rinsho 1986; 32: 1459-1465
  • 8 Miyatani H, Yoshida Y, Ushimaru S. et al. Slow growing flat-type primary malignant melanoma of the esophagus treated with cap-assisted EMR. Dig Endosc 2009; 21: 255-257
  • 9 Carr-Locke DL, Mehra K, Kumar S. et al. Primary amelanotic malignant melanoma of the esophagus. New York: Medscape LLC; 2009. Available from: http://www.medscape.com/viewarticle/712478
  • 10 Bisceglia M, Perri F, Tucci A. et al. Primary malignant melanoma of the esophagus: a clinicopathologic study of a case with comprehensive literature review. Adv Anat Pathol 2011; 18: 235-252