Kalziumhomöostase in der Multiplen Sklerose

Zusammenfassung

Kalzium ist als Signalmolkül entscheidend für nahezu alle zellulären Prozesse. Eine Störung der Kalziumhomöostase ist ursächlich für eine Vielzahl von pathologischen Zuständen. Dieser Übersichtsartikel fasst rezente Erkenntnisse über den Einfluss von Kalzium in der Multiplen Sklerose zusammen.

Abstract

Calcium is the signal molecule crucial for almost all cellular processes. Disturbances of calcium homeostasis are responsible for a variety of pathological conditions. This review article summarizes recent findings on the influence of calcium in multiple sclerosis.

Schlüsselwörter

Pathologie - Immunzellen - Blut-Hirn-Schranke - zentrales Nervensystem - speicher-abhängiger Kalziumeinstrom

Key words

pathology - immune cells - blood-brain barrier - central nervous system - store-operated calcium entry

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