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Klin Padiatr 2017; 229(03): 147-167
DOI: 10.1055/s-0043-103086
Diagnostic and Treatment Recommendation
© Georg Thieme Verlag KG Stuttgart · New York

2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors

2017 GPOH Empfehlungen für Diagnostik und Therapie von Patienten mit neuroblastischen Tumoren
Thorsten Simon
1   Department of Pediatric Oncology and Hematology, University Hospital, University of Cologne
,
Barbara Hero
1   Department of Pediatric Oncology and Hematology, University Hospital, University of Cologne
,
Johannes H. Schulte
2   Department of Pediatric Oncology and Hematology, Charité University Hospital Berlin
,
Hedwig Deubzer
2   Department of Pediatric Oncology and Hematology, Charité University Hospital Berlin
,
Patrick Hundsdoerfer
2   Department of Pediatric Oncology and Hematology, Charité University Hospital Berlin
,
Dietrich von Schweinitz
3   Department of Pediatric Surgery, Dr. von Hauner’sches Kinderspital, LMU Munich
,
Jörg Fuchs
4   Department of Pediatric Surgery and Pediatric Urology, University Hospital Tübingen
,
Matthias Schmidt
5   Department of Nuclear Medicine, University Hospital, University of Cologne
,
Vikas Prasad
6   Department of Nuclear Medicine, Charité University Hospital Berlin
,
Barbara Krug
7   Department of Radiology, University Hospital, University of Cologne
,
Beate Timmermann
8   Clinic for Particle Therapy, Westdeutsches Protonentherapiezentrum, University Hospital Essen
,
Ivo Leuschner
9   Kiel Pediatric Tumor Registry, Dept. for Pediatric Pathology, University Hospital of Schleswig-Holstein, Campus Kiel
,
Matthias Fischer
10   Department of Experimental Pediatric Oncology, University Hospital, University of Cologne
,
Thorsten Langer
11   Pediatric Oncology and Hematology, University Hospital Schleswig-Holstein, Campus Lübeck
,
Kathy Astrahantseff
2   Department of Pediatric Oncology and Hematology, Charité University Hospital Berlin
,
Frank Berthold
1   Department of Pediatric Oncology and Hematology, University Hospital, University of Cologne
,
Holger Lode
12   Department of Pediatrics and Pediatric Oncology and Hematology, University Medicine Greifswald
,
Angelika Eggert
2   Department of Pediatric Oncology and Hematology, Charité University Hospital Berlin
› Author Affiliations
Further Information

Publication History

Publication Date:
30 May 2017 (online)

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Abstract

The clinical course of neuroblastoma is more heterogeneous than any other malignant disease. Most low-risk patients experience regression after limited or even no chemotherapy. However, more than half of high-risk patients die from disease despite intensive multimodal treatment. Precise patient characterization at diagnosis is key for risk-adapted treatment. The guidelines presented here incorporate results from national and international clinical trials to produce recommendations for diagnosing and treating neuroblastoma patients in German hospitals outside of clinical trials.

Key words

neuroblastoma - ganglioneuroma - childhood cancer - treatment recommendations

Schlüsselwörter

Neuroblastom - Ganglioneurom - Behandlungsempfehlungen - Kind
 

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