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CC BY-NC-ND 4.0 · Journal of Gastrointestinal Infections 2022; 12(02): 106-111
DOI: 10.1055/s-0042-1760423
Original Article

Drug-Resistant Strains in Surgical Site Infections after Abdominal Surgery: A Prospective Study

Veenu Gupta
1   Department of Microbiology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India
,
Prateet Kaur
2   Department of Microbiology, SMS Medical College and Hospital, Jaipur, Rajasthan, India
,
Deepinder Chhina
1   Department of Microbiology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India
,
Jaspal Singh
3   Department of Surgery, Dayanand Medical College and Hospital, Ludhiana, Punjab, India
,
Rama Gupta
1   Department of Microbiology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India
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Funding None.
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Abstract

Background Surgical site infection (SSI) is a common complication of abdominal surgery associated with substantial discomfort, morbidity, and cost.

Objective The aim of this study was to determine the incidence, risk factors, and antimicrobial susceptibility pattern of the associated bacterial causes of SSI in patients after abdominal surgery.

Methods A prospective study over a 1-year (Jan 2019–Dec 2019) period was conducted at a tertiary care institution in North India. Postoperative patients of abdominal surgeries with SSI were included in the study. Any exudate from the surgical site was collected aseptically and was processed as per standard operating procedures.

Results Of 2,509 patients with abdominal surgeries included in the study, 75 (2.98%, majority, i.e., 50 males) developed SSI. Common risk factors found to be associated with the development of SSI include contaminated surgical sites, obesity, age, immunosuppression, and simultaneous infection at some other sites, with a predominance (89.3%) of gram-negative isolates. Escherichia coli was the most frequently isolated organism (45.3%), followed by Klebsiella spp. (20%), Acinetobacter spp.(10.6%), Pseudomonas spp., and Staphylococcus aureus (8% each). There was a very high (53%) prevalence of extended-spectrum β lactamase production among the E. coli and Klebsiella isolates. Additionally, 58.8% of the E. coli isolates were multidrug-resistant, whereas 73.3% of the Klebsiella isolates were exclusively drug resistant. All the S. aureus isolates were found to be methicillin-resistant.

Conclusion Although the SSI rates after abdominal surgery were low, multidrug-resistant gram-negative bacteria were predominant in SSI.

Keywords

abdominal surgeries - surgical site infection - risk factors - antimicrobila susceptibility - multidrug-resistant

Ethical Statement

Not applicable.


Author Contributions

All authors contributed equally to the article.


Data Availability Statement

There is no data associated with this work.




Publication History

Received: 09 September 2022

Accepted: 07 November 2022

Article published online:
22 September 2023

© 2023. Gastroinstestinal Infection Society of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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