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CC BY-NC-ND 4.0 · Ann Natl Acad Med Sci 2023; 59(02): 115-120
DOI: 10.1055/s-0042-1760354
Case Series

Solid Pseudopapillary Epithelial Neoplasm of the Pancreas: A Rare Entity with Diagnostic Dilemma

Sucheta Gandhe
1   Department of Pathology, HCG Manavata Cancer Centre, Nashik, Maharashtra, India
,
Rahul Patil
1   Department of Pathology, HCG Manavata Cancer Centre, Nashik, Maharashtra, India
,
Venkata Ramesh Yasam
2   Department of Academics, HCG Manavata Cancer Centre, Nashik, Maharashtra, India
,
Raj Nagarkar
3   Department of Surgical Oncology, HCG Manavata Cancer Centre, Nashik, Maharashtra, India
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Funding None.
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Abstract

The solid pseudopapillary epithelial neoplasm (SPEN) of the pancreas is a relatively uncommon entity. The aim of the present study was to summarize our experiences with regard to diagnostic dilemma, surgery, postoperative follow-up, and management. This retrospective data were collected during the period from January 1, 2018 to December 31, 2020. A total of four patients (three females and one male) were identified within an age range of 13 to 25 years. All the patients were presented with nonspecific symptoms such as abdomen lumps, swelling in the abdomen, and abdominal pain. To reach a definite diagnosis, imaging studies were conducted along with endoscopic ultrasound fine-needle aspiration (EUS-FNA) and biopsy. After confirmation of SPEN on biopsy, all the patients underwent surgery without any complications. Patients are on follow-up, and to date, no metastasis has been detected. SPEN is a rare pancreatic tumor with unusual pathological features leading to a diagnostic dilemma. The pathologist should be familiar with SPEN and its salient histological characteristics that differentiate it from other look-alike pancreatic tumors and can help in timely surgery and management.

Keywords

pancreas - solid pseudopapillary epithelial neoplasm - diagnostic dilemma - immunohistochemistry - surgery

Ethical Approval

The study followed the ethical guidelines of the Declaration of Helsinki. Written informed consent was taken from the patients for publication in the journal.




Publikationsverlauf

Artikel online veröffentlicht:
03. April 2023

© 2023. National Academy of Medical Sciences (India). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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