CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2023; 33(01): 098-100
DOI: 10.1055/s-0042-1759856
Brief Report

Effectiveness of the First Trimester Samrakshan Protocol for the Identification of Pregnant Women at High Risk for Preterm Pre-eclampsia

Rijo Mathew Choorakuttil
1   Department of Clinical Radiology, AMMA Center for Diagnosis and Preventive Medicine, Kochi, Kerala, India
Bavaharan Rajalingam
2   Department of Clinical Radiology, Fetocare Magnum Imaging and Diagnostics, Trichy, Tamil Nadu, India
Shilpa R. Satarkar
3   Department of Clinical Radiology, Antarang Sonography and Colour Doppler Center, Satarkar Hospital, Aurangabad, Maharashtra, India
Lalit K. Sharma
4   Department of Clinical Radiology, Raj Sonography and X- Ray Clinic, Guna, Madhya Pradesh, India
Anjali Gupta
5   Department of Clinical Radiology, Anjali Ultrasound and Colour Doppler Centre, Agra, Uttar Pradesh, India
Akanksha Baghel
6   Department of Clinical Radiology, Baghel Sonography Center, Harda, Madhya Pradesh, India
Neelam Jain
7   Department of Clinical Radiology, Department of Radiodiagnosis, Jain Ultrasound Centre, Jamshedpur, Jharkhand, India
Sandhya Dhankar
8   Department of Clinical Radiology, Faith Diagnostic Center, Chandigarh, India
9   Department of Clinical Radiology, Images Ultrasound Center, Naveda Healthcare Centre, New Delhi, India
Gulab Chhajer
10   Department of Clinical Radiology, Department of Radiodiagnosis, Kushal Imaging and Diagnostic Center, Pali, Rajasthan, India
Somya Dwivedi
11   Department of Clinical Radiology, Qura Diagnostics and Research Center, Bhopal, Madhya Pradesh, India
Tejashree Y. Patekar
12   Department of Clinical Radiology, Innovision Sonography and Imaging Center, Gangapur, Nashik, India
Eesha Rajput
13   Department of Clinical Radiology, INHS Asvini, Mumbai, Maharashtra, India
14   Department of Research, AMMA Healthcare Research Gurukul, AMMA Center for Diagnosis and Preventive Medicine, Kochi, Kerala, India
› Author Affiliations


Aim To determine the effectiveness of the first trimester Samrakshan protocol for the identification of pregnant women at high risk for preterm pre-eclampsia (PE).

Methods Samrakshan uses a protocol that integrates routine first-trimester ultrasound assessment at 11 to 14 gestation weeks with the measurement of mean arterial blood pressure and mean uterine artery pulsatility index assessment to determine a customized risk for preterm PE and fetal growth restriction. Based on the risk assessment, pregnant women are classified as high or low risk.

Results The protocol had a high specificity (90.4%, 95% CI: 89.4%, 91.2%) and negative predictive value (98.1%, 95% CI: 97.6%, 99%) for preterm PE. The odds ratio and positive likelihood ratio for preterm PE were 16.7 (95% CI: 12.3, 22.6) and 6.64 (95% CI: 5.77, 7.63), respectively.

Conclusions The positive likelihood ratio and odds ratios indicate that pregnant women identified as high risk for preterm PE using the first-trimester protocol of Samrakshan are significantly more likely to develop preterm PE than low-risk women.

Publication History

Article published online:
26 December 2022

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