RSS-Feed abonnieren

DOI: 10.1055/s-0042-1759787
Editorial: Prerequisites for a Successful Probiotic Therapy in Dysbiosis
Funding None.

This article briefly addresses why many forms of probiotic treatment are unsound and provides a set of prerequisites to increase the effectiveness of improved probiotic delivery. We pay particular attention to why probiotics largely fail, then suggest prerequisite principles that favor successful long-term engraftment.
Ethical Statement
Not applicable.
Author Contributions
All authors contributed equally to the article.
Data Availability Statement
There is no data associated with this work.
Publikationsverlauf
Eingereicht: 17. Oktober 2022
Angenommen: 19. Oktober 2022
Artikel online veröffentlicht:
22. September 2023
© 2023. Gastroinstestinal Infection Society of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Zmora N, Zilberman-Schapira G, Suez J. et al. Personalized gut mucosal colonization resistance to empiric probiotics is associated with unique host and microbiome features. Cell 2018; 174 (06) 1388-1405.e21
- 2 McFarland LV. Probiotics for the primary and secondary prevention of C. difficile infections: a meta-analysis and systematic review. Antibiotics (Basel) 2015; 4 (02) 160-178
- 3 Allen SJ, Wareham K, Wang D. et al. Lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in older inpatients (PLACIDE): a randomised, double-blind, placebo-controlled, multicentre trial. Lancet 2013; 382 (9900): 1249-1257
- 4 Goldenberg JZ, Yap C, Lytvyn L. et al. Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children. Cochrane Database Syst Rev 2017; 12 (12) CD006095
- 5 Shogbesan O, Poudel DR, Victor S. et al. A systematic review of the efficacy and safety of fecal microbiota transplant for Clostridium difficile infection in immunocompromised patients. Can J Gastroenterol Hepatol 2018; 2018: 1394379
- 6 Quraishi MN, Widlak M, Bhala N. et al. Systematic review with meta-analysis: the efficacy of faecal microbiota transplantation for the treatment of recurrent and refractory Clostridium difficile infection. Aliment Pharmacol Ther 2017; 46 (05) 479-493
- 7 Kristensen NB, Bryrup T, Allin KH, Nielsen T, Hansen TH, Pedersen O. Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials. Genome Med 2016; 8 (01) 52
- 8 Smillie CS, Sauk J, Gevers D. et al. Strain-tracking reveals the determinants of bacterial engraftment in the human gut following fecal microbiota transplantation. Cell Host Microbe 2018; 23 (02) 229-240.e5
- 9 Kapourchali FR, Cresci GAM. Early-life gut microbiome-the importance of maternal and infant factors in its establishment. Nutr Clin Pract 2020; 35 (03) 386-405
- 10 Kong L, Lloyd-Price J, Vatanen T. et al. Linking strain engraftment in fecal microbiota transplantation with maintenance of remission in Crohn's disease. Gastroenterology 2020; 159 (06) 2193-2202.e5
- 11 Bajaj JS, Kassam Z, Fagan A. et al. Fecal microbiota transplant from a rational stool donor improves hepatic encephalopathy: a randomized clinical trial. Hepatology 2017; 66 (06) 1727-1738
- 12 Cammarota G, Ianiro G, Tilg H. et al; European FMT Working Group. European consensus conference on faecal microbiota transplantation in clinical practice. Gut 2017; 66 (04) 569-580
- 13 Wilson BC, Vatanen T, Cutfield WS, O'Sullivan JM. The super-donor phenomenon in fecal microbiota transplantation. Front Cell Infect Microbiol 2019; 9: 2
- 14 Vermeire S, Joossens M, Verbeke K. et al. Donor species richness determines faecal microbiota transplantation success in inflammatory bowel disease. J Crohn's Colitis 2016; 10 (04) 387-394
- 15 Han C, Song J, Hu J. et al. Smectite promotes probiotic biofilm formation in the gut for cancer immunotherapy. Cell Rep 2021; 34 (06) 108706
- 16 Tariq R. Systematic review and meta-analysis: safety and efficacy of Saccharomyces boulardii for prevention of Clostridioides difficile infection. J Gastrointest Infect 2022; 12 (02) 94-100