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Quantification of Porphyromonas gingivalis Bacteria in Final Trimester of Pregnant Women According to Their Oral Health StatusFunding This research supported by Universitas Airlangga in the Schema Hibah Riset Mandat 2018 with number 886/UN3/2018.
Objective Pregnant women are more at risk to suffer dental infection. Untreated dental infection during pregnancy can lead to more serious problems to mothers and their children, such as premature birth and low birth weight. This study aims to analyzed the relationship between oral hygiene status (OHI-S) and the expression of Porphyromonas gingivalis in third trimester pregnant women.
Materials and Methods This was an observational analytic study with a cross-sectional study design. Patients consisted of 37 final trimester pregnant women, divided into good OHI-S and fair OHI-S. The P. gingivalis expression was measured using real-time qPCR from the mucosal swab.
Results The P. gingivalis expression found no differences between good OHI-s and fair OHI-S (p = 0.557).
Conclusion Based on this study, although there was no significant difference in P. gingivalis expression in the final trimester based on their oral health status, oral health is considered important to be taken care of during pregnancy.
Article published online:
04 January 2023
© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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- 1 Baiju RM, Peter E, Varghese NO, Sivaram R. Oral health and quality of life: current concepts. J Clin Diagn Res 2017; 11 (06) ZE21-ZE26
- 2 Kementerian Kesehatan RI. Hasil Utama Riset Kesehatan Dasar. Kementrian Kesehatan Republik Indonesia; 2018. :1–100
- 3 Bozorgmehr E, Bamedi M, Khalili S, Ansari H. Relationship between the oral hygiene index (OHI-S) and demographic characteristics of pregnant women referred to health centers in Zahedan, 2016. Dental Clinical and Experimental Journal. 2019; 4 (01) 1-5
- 4 Rakchanok N, Amporn D, Yoshida Y, Harun-Or-Rashid M, Sakamoto J. Dental caries and gingivitis among pregnant and non-pregnant women in Chiang Mai, Thailand. Nagoya J Med Sci 2010; 72 (1-2): 43-50
- 5 Doucède G, Dehaynin-Toulet E, Kacet L. et al. Dents et grossesse, un enjeu de santé publique. Presse Med 2019; 48 (10) 1043-1050
- 6 Jithendra K, Bansali A, Ramachandra S. Failures in periodontal therapy. Bangladesh Journal of Medical Science. 2010; 9 (04) 193-198
- 7 Cafiero C, Matarasso S. Predictive, preventive, personalised and participatory periodontology: ‘the 5Ps age’ has already started. EPMA J 2013; 4 (01) 16
- 8 Fujiwara N, Tsuruda K, Iwamoto Y. et al. Significant increase of oral bacteria in the early pregnancy period in Japanese women. J Investig Clin Dent 2017; 8 (01) 1-8
- 9 Marakoglu I, Gursoy UK, Marakoglu K, Cakmak H, Ataoglu T. Periodontitis as a risk factor for preterm low birth weight. Yonsei Med J 2008; 49 (02) 200-203
- 10 Uriza CL, Velosa-Porras J, Roa NS. et al. Periodontal disease, inflammatory cytokines, and PGE2 in pregnant patients at risk of preterm delivery: a pilot study. Ramsey P, ed. Infect Dis Obstet Gynecol 2018;2018:7027683
- 11 Tomás I, Regueira-Iglesias A, López M. et al. Quantification by qPCR of pathobionts in chronic periodontitis: development of predictive models of disease severity at site-specific level. Front Microbiol 2017; 8 (AUG): 1443
- 12 Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Δ C(T)) Method. Methods 2001; 25 (04) 402-408
- 13 Jang H, Patoine A, Wu TT, Castillo DA, Xiao J. Oral microflora and pregnancy: a systematic review and meta-analysis. Sci Rep 2021; 11 (01) 16870
- 14 Massoni RSS, Aranha AMF, Matos FZ. et al. Correlation of periodontal and microbiological evaluations, with serum levels of estradiol and progesterone, during different trimesters of gestation. Sci Rep 2019; 9 (01) 11762
- 15 Kurniawan FKD, Roestamadji RI, Takahashi N. et al. Oral microbiome profiles and inflammation in pregnant women who used orthodontic appliances. Dent J 2022; 10 (07) 118
- 16 Carrillo-de-Albornoz A, Figuero E, Herrera D, Cuesta P, Bascones-Martínez A. Gingival changes during pregnancy: III. Impact of clinical, microbiological, immunological and socio-demographic factors on gingival inflammation. J Clin Periodontol 2012; 39 (03) 272-283
- 17 Lee DK, In J, Lee S. Standard deviation and standard error of the mean. Korean J Anesthesiol 2015; 68 (03) 220-223