Abstract
In recent years and for decades, antimicrobial resistance (AMR) has expanded into
a major clinical issue. Infections were no longer a life-threatening issue for clinicians
after the discovery of antibiotics. The misuse or overuse of antibiotics, however,
contributes to global AMR, and numerous mobile genetic elements and relevant resistant
genes worsen the spread of resistance. As antibiotics lose their effectiveness, a
growing number of infections such as pneumonia, tuberculosis, and gonorrhea are getting
harder and sometimes impossible to treat. Infections that are resistant to antibiotics
are correlated with antibiotic misuse. The majority of the antibiotic resistance in
microbes is caused by improper use of antibiotics. Because there are a few antibiotics
available to treat multidrug-resistant bacterial infections, there is a high rate
of morbidity and mortality. Libya has a high burden of antibiotic resistance, and
antimicrobial malpractice has frequently been reported. Providing information on the
current state of antimicrobial resistance in Libya may assist the health authorities
in addressing the problem more effectively in the future. Therefore, this review highlights
the current situation of bacterial profile and their antimicrobial resistance in Libya
based on the source of infection. Articles related to the topic were searched using
databases and search engines such as PubMed, Google Scholar, and ResearchGate websites.
These articles were selected if they were conducted in Libya and provided information
on bacterial pathogens and AMR. Required data were extracted for the purpose of this
review report, and then further verified for identifying the prevalence and number
of susceptible and resistant pathogens in each source of infection.
Keywords
bacteria - antibiotic - microbial resistance - infection - Libya
