A new alkaloid from Scadoxus multiflorus

Scadoxus multiflorus (Martyn) Raf. (Amaryllidaceae) or blood lily is an ornamental plant native to tropical and southern Africa. It is traditionally used in the treatment of many respiratory problems (bronchitis, asthma, pneumonia, etc.), scabies, dropsy, and wound healing [1]. However, the alkaloidal constituents of S. multiflorus have rarely been explored and only a few are known [2], [3]. In the course of our study of Amaryllidaceae alkaloids, a full investigation of the alkaloidal profile of bulbs of S. multiflorus was carried out using a combination of chromatographic and spectroscopic techniques, as well as computational calculations. As a result, a previously undescribed alkaloid (1), together with 14 known ones (lycorine, 2-O-methylpseudolycorine, narciclasine, lycoricidine, ungiminorine, ungiminorine N-oxide, narcissidine, sanguinine, montanine, 2-O-acetyl-chlidanthine, 2-hydroxy-O,N-dimethylnorbelladine, O-demethylmaritidine, 8-O-demethyloxomaritidine, 9-de-O-methyl-11β-hydroxygalanthamine), were isolated and characterized.

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Publication History

Article published online:
12 December 2022

• References

• 1 Monkheang P, Chaveerach A, Sudmoon R, Tanee T. . Comp Cytogenet 2016; 10: 637-646
• 2 Aliero A, Aliero BL, Buhari U. . Int J Pure Appl Sci 2008; 2: 13-17
• 3 Cahlíková L, Benešová N, Macáková K. et al. Nat Pro Coms. 2011; 6-9