Planta Med 2022; 88(15): 1431
DOI: 10.1055/s-0042-1758986
Short Lectures F: Animal Health care

Short Lecture “The effect of Melissa officinalis extract and chlorogenic acid on intestine motility of broiler chicken – ex vivo study”

M Posłuszny
1   Warsaw University of Life Sciences, Institute of Veterinary Medicine, Warsaw, Poland
,
M Chłopecka
1   Warsaw University of Life Sciences, Institute of Veterinary Medicine, Warsaw, Poland
,
S Suor-Cherer
2   Labcom FeedInTech, Beaucouzé, France
3   Nor-Feed SAS, France
,
M el Amine Benarbia
2   Labcom FeedInTech, Beaucouzé, France
3   Nor-Feed SAS, France
,
M Mendel∗
1   Warsaw University of Life Sciences, Institute of Veterinary Medicine, Warsaw, Poland
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Melissa officinalis is a very common herb with high palatability. It also has a long history of being used in traditional medicine. This study aimed to develop knowledge about Melissa extract and its main active substances in regards to broilers intestine contractility – proximal and distal part of jejunum.

Materials and methods: The experiments were conducted on longitudinal jejunum samples collected from routinely slaughtered birds on two different parts of the jejunum: proximally and distally to Meckel diverticulum. The effect of standardized Melissa officinalis extract (Nor-Balm®) [1] and chlorogenic acid on spontaneous and ACh-induced activity was evaluated under isometric conditions [2].

Results: The results revealed dose-dependent potency of Melissa extract to increase the magnitude of acetylcholine-induced contraction. Besides, the extract enhanced spontaneous contractility in distal part of the jejunum but reduced this strength in proximal part. In case of chlorogenic acid the spontaneous motility in both parts was dose-dependently decreased. Chlorogenic acid inhibited remarkably the contraction induced by ACh in both parts.

Conclusions: The results of the performed study indicate that Melissa officinalis can be used to control gastrointestinal motility in chicken. Its ability to limit the size of ACh-induced contractility might be beneficial in hypermotility disorders in broilers. It seems that chlorogenic acid does not contribute to the final effect of the plant extract what proves more complex interaction and probable contribution of other phytoconstituents.



Publication History

Article published online:
12 December 2022

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  • References

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