CC BY-NC-ND 4.0 · Asian J Neurosurg 2022; 17(04): 621-630
DOI: 10.1055/s-0042-1757437
Original Article

Study of Association of Various Psychiatric Disorders in Brain Tumors

Achal Sharma
1   Department of Neurosurgery, SMS Medical College and Hospital, Jaipur, Rajasthan, India
,
2   Department of Neurosurgery, All India Institute of Medical Sciences, Patna, Bihar, India
,
Akhilesh Jain
3   Department of Psychiatry, ESIC Model Hospital, Jaipur, Rajasthan, India
,
Devendra Kumar Purohit
1   Department of Neurosurgery, SMS Medical College and Hospital, Jaipur, Rajasthan, India
,
Ram Kumar Solanki
4   Department of Psychiatry, SMS Medical College and Hospital, Jaipur, Rajasthan, India
,
Ajay Gupta
5   Department of Preventive and Social Medicine, SMS Medical College and Hospital, Jaipur, Rajasthan, India
› Author Affiliations
Funding None.

Abstract

Background Brain tumors may be associated with high morbidity, and psychiatric symptoms may be an early manifestation. It is important to address mental symptoms as early as possible because they are prone to develop psychiatric comorbidities in future. If untreated, these situations may worsen and lead to burden upon caregivers.

Methods A total of 176 brain tumor patients between January 2021 and January 2022 constituted the sample size. All recently diagnosed cases of brain tumor with age equal to or more than 18 years who can comprehend and answer questionnaires were included. Patients with a long history of brain tumor or who had a history of a psychiatric illness other than presenting symptoms or any other serious medical illness were excluded.

Results Twenty-seven percent of brain tumor patients had psychiatric symptoms. Depressive symptoms were the most common, associated with 24% of patients, followed by anxiety disorders. Psychiatric disorders were more common in supratentorial compared to infratentorial tumors. Psychiatric symptoms seem to be associated more commonly with malignant tumors and peritumoral edema. Among malignant tumors, depressive symptoms tend to be related with high-grade glioma, and among benign tumors, they were more common in meningioma. No predilection to laterality and anatomical lobe involvement is reported.

Conclusion Screening of psychiatric disorders should be a routine in brain tumor patients. An integrated approach is required to treat brain tumor patients. Healthcare professionals should be more vigilant about the onset of psychiatric symptoms and the need of palliative care to improve the quality of life.

Authors' Contributions

All authors contributed to the study conception and design. Material preparation, data collection, and analysis were performed by Anand K. Das, Achal Sharma, Akhilesh Jain, Devendra K. Purohit, Ram K. Solanki, and Ajay Gupta. The first draft of the manuscript was written by Anand K. Das and all authors commented on previous versions of the manuscript. All authors read and approved the final version of manuscript.


Ethical Approval

The study was approved by the Institution's Ethics Committee (Protocol No. 309 MC/EC/2021).


Data Availability

The data associated with the paper are not publicly available but are available from the corresponding author on reasonable request.


Supplementary Material



Publication History

Article published online:
28 October 2022

© 2022. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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