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CC BY 4.0 · Journal of Digestive Endoscopy 2022; 13(04): 240-242
DOI: 10.1055/s-0042-1756483
Review Article

Endoscopic Ultrasound Biopsy Needle

Nikhil Bush
1   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
,
Surinder Singh Rana
1   Department of Gastroenterology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Abstract

In the past few years, endoscopic ultrasound (EUS)-guided fine-needle biopsy (EUS-FNB) has superseded EUS-fine-needle aspiration (EUS-FNA) for EUS-guided tissue acquisition. EUS-FNA does not retain the stroma as well as the surrounding tissue architecture and therefore had limitations in achieving a definitive diagnosis. Development of EUS-FNB needles had improved the diagnostic ability of EUS by providing core tissue sample that not only preserves surrounding tissue architecture but also provides adequate material for molecular typing and gene profiling of sampled lesions. At present, there are three commercially available third-generation EUS-FNB needles with unique needle tip designs. In this review, we aim to elucidate the technical aspects of the available EUS-FNB needles.

Keywords

Endoscopic ultrasound (EUS) - Fine needle aspiration (FNA) - Fine needle biopsy (FNB) - Tissue - Pancreatic

Authors' Contributions

Nikhil Bush contributed to collection and interpretation of data and drafting of manuscript.

Surinder Singh Rana was involved in collection and interpretation of data, drafting as well as critical evaluation of manuscript for intellectual content.




Publication History

Article published online:
15 December 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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