CC BY 4.0 · Eur J Dent 2023; 17(01): 016-023
DOI: 10.1055/s-0042-1755625
Review Article

Potential Use of Hyperbaric Oxygen Therapy in Orthodontic Treatment: A Systematic Review of Animal Studies

Yun Mukmin Akbar
1   Doctoral Program, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia
2   Department of Research Development, Indonesian Naval Dental Institute R.E. Martadinata, Jakarta, Indonesia
,
Ani Melani Maskoen
3   Department of Oral Biology, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia
,
Endah Mardiati
4   Department of Orthodontics, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia
,
Ganesha Wandawa
2   Department of Research Development, Indonesian Naval Dental Institute R.E. Martadinata, Jakarta, Indonesia
,
5   Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Padjadjaran, Bandung, Indonesia
› Author Affiliations
Funding None.

Abstract

Understanding the fundamental principles of tooth movement could reduce the duration of treatment and achieve a stable outcome, resulting in patient satisfaction. Hyperbaric oxygen therapy was a modality in which a patient inhaled 100% O2 while subjected to high atmospheric pressure. Hyperbaric oxygen therapy facilitated the supply of oxygen to the human body's organs and tissues and served a variety of applications, including patient care and wound treatment. This review article aimed to describe animal studies of the potential effects of hyperbaric oxygen therapy in orthodontic therapy. It was conducted using a systematic literature review method, including searching PubMed and Google Scholar for publications relevant to the research topics. The search was filtered to include only research on orthodontic treatment and hyperbaric oxygen therapy and was published in any year. Articles that did not specify biological components of orthodontic tooth movement (OTM) were excluded. The Preferred Reporting Items identified the papers for the Systematic Reviews and Meta-Analyses (PRISMA) strategy, which resulted in the selection of 11 publications. Hyperbaric oxygen therapy affected parameters of biomarkers representing the clinical, molecular, and cellular biology of bone formation and resorption in periodontal tissues in responding to orthodontic physical forces, including alkaline phosphatase, collagen synthesis, osteoblast, osteoclast, osteocyte, type I collagen, vascular endothelial growth factor, osteocalcin, fibroblast, matrix metalloproteinase-8, transforming growth factor-β, partial pressure of oxygen, partial pressure of carbon dioxide, trabecular bone density, and tooth mobility. Hyperbaric oxygen therapy induced an inflammatory response to follow OTM events during active orthodontic therapy. Hyperbaric oxygen therapy might play a role in the tissue healing process during passive treatment. Nonetheless, additional research should be conducted to establish the efficacy of hyperbaric oxygen therapy in orthodontics.

Authors' Contributions

All authors in this study admit to their involvement in the manuscript's creation stages. Y.M.A. conceived the ideas. Y.M.A., A.M.M., E.M., and G.W. gathered and processed data. Finally, Y.M.A. and A.S.S. helped finalize the manuscript.




Publication History

Article published online:
11 October 2022

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  • References

  • 1 Proffit W. Contemporary Orthodontics. 5th ed. Published by Oxford University Press on behalf of the European Orthodontic Society. St. Louis, MO: Elsevier Inc.; 2012
  • 2 Asiry MA. Biological aspects of orthodontic tooth movement: a review of literature. Saudi J Biol Sci 2018; 25 (06) 1027-1032
  • 3 Thilander B, Erik BL. Bondemark. Essential Orthodontics. 1st ed. London: John Wiley & Sons, Inc.; 2018
  • 4 Weed T, Bill T, Gampper TJ. Hyperbaric oxygen therapy. In: Biomedical Technology and Devices Handbook. 2nd ed. London, UK: CRC Press; 2003
  • 5 Sen CK. Wound healing essentials: let there be oxygen. Wound Repair Regen 2009; 17 (01) 1-18
  • 6 Thom SR. Oxidative stress is fundamental to hyperbaric oxygen therapy. J Appl Physiol 2009; 106 (03) 988-995
  • 7 Fosen KM, Thom SR. Hyperbaric oxygen, vasculogenic stem cells, and wound healing. Antioxid Redox Signal 2014; Oct 10; 21 (11) 1634-1647
  • 8 Thom SR. Hyperbaric oxygen: its mechanisms and efficacy. Plast Reconstr Surg 2011; 127 (Suppl. 1 S): 131S-141S
  • 9 Re K, Patel S, Gandhi J. et al. Clinical utility of hyperbaric oxygen therapy in dentistry. Med Gas Res 2019; 9 (02) 93-100
  • 10 Dhammi IK, Haq RU. How to write systematic review or metaanalysis. Indian J Orthop 2018; 52 (06) 575-577
  • 11 Aslam S, Emmanuel P. Formulating a researchable question: a critical step for facilitating good clinical research. Indian J Sex Transm Dis AIDS 2010; 31 (01) 47-50
  • 12 Sadida ZJ, Indriyanti R, Setiawan AS. Does growth stunting correlate with oral health in children?: a systematic review. Eur J Dent 2022; 16 (01) 32-40
  • 13 D'Apuzzo F, Cappabianca S, Ciavarella D, Monsurrò A, Silvestrini-Biavati A, Perillo L. Biomarkers of periodontal tissue remodeling during orthodontic tooth movement in mice and men: overview and clinical relevance. ScientificWorldJournal 2013;2013:105873
  • 14 Brooks PJ, Nilforoushan D, Manolson MF, Simmons CA, Gong SG. Molecular markers of early orthodontic tooth movement. Angle Orthod 2009; 79 (06) 1108-1113
  • 15 Feller L, Khammissa RA.G, Schechter I, Moodley A, Thomadakis G, Lemmer J. Periodontal biological events associated with orthodontic tooth movement: the biomechanics of the cytoskeleton and the extracellular matrix. ScientificWorldJournal 2015;2015:894123
  • 16 Tuncay OC, Ho D, Barker MK. Oxygen tension regulates osteoblast function. Am J Orthod Dentofacial Orthop 1994; 105 (05) 457-463
  • 17 Prameswari N, Revianti S, Ajeng C, Azania H, Leona C. Osteogenesis and osteoclastogenesis regulation of the midpalatal area after maxillary suture expansion induced by hyperbaric oxygen therapy (HBOT). Malaysian J Med Health Sci 2020; 16 (04) 52-59
  • 18 Prayogo RD, Sandy BN, Sujarwo H. et al. The changes of fibroblast and periodontal ligament characteristics in orthodontic tooth movement with adjuvant HBOT and propolis: a study in guinea pigs. Padjadjaran J Dentis 2020; 32 (01) 48
  • 19 Jonathan IN, Brahmanta A, Rahardjo P. The influence of hyperbaric oxygen therapy to osteocyte cell number on pressure side during orthodontic tooth movement. Denta 2015; 9 (02) 180
  • 20 Brahmanta A. Soetjipto NIB. The expression of collagen type-I in the tension area of orthodontic tooth movement with adjuvant hyperbaric oxygen therapy. Int J Chemtech Res 2016; 9 (07) 199-204
  • 21 Brahmanta A, Prameswari N. VEGF regulates osteoblast differentiation in tension and pressure regions orthodontic tooth movement administered with hyperbaric oxygen therapy. J Int Dental Med Res 2019; (04) 1382-1388
  • 22 Brahmanta A, Prameswari N, Handayani B, Syahdinda MR. The effect of hyperbaric oxygen 2.4 absolute atmospheres on transforming growth factor-β and matrix metalloproteinase-8 expression during orthodontic tooth movement in vivo. J Pharm Pharmacogn Res 2021; 9 (04) 517-524
  • 23 Gokce S, Bengi AO, Akin E. et al. Effects of hyperbaric oxygen during experimental tooth movement. Angle Orthod 2008; 78 (02) 304-308
  • 24 Inokuchi T, Kawamoto T, Aoki K. et al. The effects of hyperbaric oxygen on tooth movement into the regenerated area after distraction osteogenesis. Cleft Palate Craniofac J 2010; 47 (04) 382-392
  • 25 Salah H, Eid ED. Effect of hyperbaric oxygen on mobility of orthodontically treated teeth. Egypt Orthod J 2010; 38 (December): 107-124
  • 26 Wise GE, King GJ. Mechanisms of tooth eruption and orthodontic tooth movement. J Dent Res 2008; 87 (05) 414-434
  • 27 Krishnan V, Davidovitch Z. Cellular, molecular, and tissue-level reactions to orthodontic force. Am J Orthod Dentofacial Orthop 2006; 129 (04) 469.e1-469.e32
  • 28 Masella RS, Meister M. Current concepts in the biology of orthodontic tooth movement. Am J Orthod Dentofacial Orthop 2006; 129 (04) 458-468
  • 29 Iwasaki LR, Gibson CS, Crouch LD, Marx DB, Pandey JP, Nickel JC. Speed of tooth movement is related to stress and IL-1 gene polymorphisms. Am J Orthod Dentofacial Orthop 2006; 130 (06) 698.e1-698.e9
  • 30 von Böhl M, Maltha JC, Von Den Hoff JW, Kuijpers-Jagtman AM. Focal hyalinization during experimental tooth movement in beagle dogs. Am J Orthod Dentofacial Orthop 2004; 125 (05) 615-623
  • 31 Rygh P. Elimination of hyalinized periodontal tissues associated with orthodontic tooth movement. Scand J Dent Res 1974; 82 (01) 57-73
  • 32 Krishnan V, Kulipers-Jagtman AM, Davidovitch Z. Biological Mechanisms of Tooth Movement. 2nd ed.. London: John Wiley & Sons, Ltd.; 2015
  • 33 Miyagawa A, Chiba M, Hayashi H, Igarashi K. Compressive force induces VEGF production in periodontal tissues. J Dent Res 2009; 88 (08) 752-756
  • 34 Moslehi J, Rathmell WK. The 2019 Nobel Prize honors fundamental discoveries in hypoxia response. J Clin Invest 2020; 130 (01) 4-6
  • 35 Semenza GL. Oxygen sensing, homeostasis, and disease. N Engl J Med 2011; 365 (06) 537-547
  • 36 Rey S, Semenza GL. Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling. Cardiovasc Res 2010; 86 (02) 236-242
  • 37 Gordillo GM, Sen CK. Revisiting the essential role of oxygen in wound healing. Am J Surg 2003; 186 (03) 259-263
  • 38 Roy S, Khanna S, Bickerstaff AA. et al. Oxygen sensing by primary cardiac fibroblasts: a key role of p21(Waf1/Cip1/Sdi1). Circ Res 2003; 92 (03) 264-271
  • 39 Sheikh AY, Gibson JJ, Rollins MD, Hopf HW, Hussain Z, Hunt TK. Effect of hyperoxia on vascular endothelial growth factor levels in a wound model. Arch Surg 2000; 135 (11) 1293-1297
  • 40 Bishop A. Role of oxygen in wound healing. J Wound Care 2008; 17 (09) 399-402
  • 41 Rodriguez PG, Felix FN, Woodley DT, Shim EK. The role of oxygen in wound healing: a review of the literature. Dermatol Surg 2008; 34 (09) 1159-1169
  • 42 Prameswari N, Sunaryo IR, Damayanti DW, Febrina A. The influence of hyperbaric oxygen therapy (HBOT) to intercausal relationship between blood vessels, osteoblast, and new bone formation during maxillary suture expansion. Padjadjaran J Dentist 2020; 32 (01) 14-21
  • 43 Maeda H, Tomokiyo A, Fujii S, Wada N, Akamine A. Promise of periodontal ligament stem cells in regeneration of periodontium. Stem Cell Res Ther 2011; 2 (04) 33
  • 44 Redlich M, Palmon A, Zaks B, Geremi E, Rayzman S, Shoshan S. The effect of centrifugal force on the transcription levels of collagen type I and collagenase in cultured canine gingival fibroblasts. Arch Oral Biol 1998; 43 (04) 313-316
  • 45 Redlich M, Shoshan S, Palmon A. Gingival response to orthodontic force. Am J Orthod Dentofacial Orthop 1999; 116 (02) 152-158