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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2022; 32(03): 416-421
DOI: 10.1055/s-0042-1753466
Case Report

Unleashing the Mystery of a Treated Case of Medulloblastoma

Renuka M. Ashtekar 
1   Department of Radiology, Tata Memorial Centre and Homi Bhabha National Institute, Mumbai, Maharashtra, India
,
Sridhar Epari
2   Department of Pathology, Tata Memorial Centre and Homi Bhabha National Institute, Mumbai, Maharashtra, India
,
Prakash M. Shetty
3   Department of Neurosurgery, Tata Memorial Centre and Homi Bhabha National Institute, Mumbai, Maharashtra, India
,
Arpita A. Sahu 
1   Department of Radiology, Tata Memorial Centre and Homi Bhabha National Institute, Mumbai, Maharashtra, India
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Abstract

Medulloblastoma (MB) is the most common malignant brain tumor in children. Despite advancement in treatment modalities, recurrence remains common, even among those treated with a combination of neurosurgery, craniospinal irradiation, and chemotherapy. The diagnosis of recurrence is usually not difficult in these cases. However, it may pose a challenge in cases with unusual clinical presentation and imaging. Imaging findings on magnetic resonance imaging, with application of perfusion, in conjunction with positron emission tomography-computed tomography can help in clinching the diagnosis in such cases. MB subgroups show consistent patterns even in cases of recurrence, and sonic hedgehog group MB may present as local recurrence showing enhancement with no diffusion restriction, as demonstrated in this case.

Keywords

recurrent medulloblastoma - radiation-induced demyelination - radiation-induced glioma - MR perfusion

Presentation at a Meeting

Nil.


Source(s) of Support

Nil.




Publication History

Article published online:
31 July 2022

© 2022. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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