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CC BY 4.0 · Journal of Child Science 2022; 12(01): e83-e88
DOI: 10.1055/s-0042-1751270
Original Article

A Retrospective Analysis of Retinopathy of Prematurity (ROP) in a Tertiary Newborn Intensive Care Unit: Incidence and Risk Factors of ROP

Fatih Varol 
1   Department of Pediatrics, Suleymaniye Obstetrics and Child Health Training and Research Hospital, University of Health Sciences, Istanbul, Turkey
,
Tulin Ogreten 
2   Division of Ophthalmology, Department of Pediatrics, Suleymaniye Obstetrics and Child Health Training and Research Hospital, University of Health Sciences, Istanbul, Turkey
,
Tutku Ozdogan 
3   Division of NICU, Department of Pediatrics, Suleymaniye Obstetrics and Child Health Training and Research Hospital, University of Health Sciences, Istanbul, Turkey
,
Serdar Cömert 
3   Division of NICU, Department of Pediatrics, Suleymaniye Obstetrics and Child Health Training and Research Hospital, University of Health Sciences, Istanbul, Turkey
,
Nedim Samancı 
3   Division of NICU, Department of Pediatrics, Suleymaniye Obstetrics and Child Health Training and Research Hospital, University of Health Sciences, Istanbul, Turkey
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Abstract

Background Retinopathy of prematurity (ROP) is the most frequent problem which causes blindness in preterm babies. In our study we evaluate the frequency of retinopathy, the risk factors, and their effects on disease development in premature newborns admitted to our neonatal intensive care unit (NICU).

Methods A total of 139 premature infants with gestational ages less than 34 weeks followed in our NICU between January 1, 2008 and January 1, 2011. The infants were divided into two groups as group 1 (no ROP/mild ROP) and as group 2 (severe ROP).

Results The demographics of 139 patients were as follows: 79 (56.83%) were female and 60 (43.17%) were male. Overall, 104 (74.8%) patients were found to have no or mild ROP and 35 (25.2%) had severe ROP. Among the patients in the severe ROP group, 25 of them had plus disease. With logistic regression analysis, lower gestational age (odds ratio [OR]: 4.1, confidence interval [CI]: 1.9–9.2), the central catheter usage (OR: 13.4, CI: 1.2–146.6), hypotension (OR: 7.5, CI: 1.1–49.6), perinatal asphyxia (OR: 261.3, CI: 8.8–7725.4), apnea (OR: 18.1, CI: 1.6–202.6), and high FiO2 (OR: 1.2 CI: 1.0–1.5) were found to be related to severe ROP.

Conclusion Among the preterms with very low body weight included in our study, we found that the frequency of severe ROP requiring treatment was low. The most important factors related to severe ROP were found to be low gestational age and birth weight. Being aware of the risk factors related to severe ROP in addition to screening every preterm infant carrying these risk factors is extremely important for the early diagnosis and treatment to prevent blindness due to severe retinopathy.

Keywords

NICU - ROP - prematurity


Publication History

Received: 05 February 2022

Accepted: 08 May 2022

Article published online:
15 September 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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