Subscribe to RSS
Challenging Management of Large Aggressive Fibromatosis of the Anterior Abdominal Wall: A Case Report
Aggressive fibromatosis is a rare and benign tumor of soft tissues, locally invasive but never metastasizes. This proliferation arises in musculoaponeurotic structures. It is more common in young fertile women due to hormonal influences. Radical resection with free margins is the key to an effective outcome. We present here the case of a 47-year-old woman, without medical history, who was referred to our hospital for a painful swelling of the left iliac fossa, diagnosed with aggressive fibromatosis of the anterior abdominal wall based on radiological and histological findings. She underwent an excision of the mass with free margins followed by reconstruction of the musculo-fascial defect. After a follow-up of 12 months, there was no evidence of recurrence. Management of aggressive fibromatosis remains a challenge for surgeons. Complete excision of the tumor followed by reconstruction of abdominal wall defect is the first choice of treatment.
Authors have declared that no competing interests exist.
Article published online:
01 July 2022
© 2022. Spring Hope Cancer Foundation & Young Oncologist Group of Asia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
- 1 Spear MA, Jennings LC, Mankin HJ. et al. Individualizing management of aggressive fibromatoses. Int J Radiat Oncol Biol Phys 1998; 40 (03) 637-645
- 2 Fletcher CDM, Bridge JA, Hogendoorn PCW. et al. IARC and Lyon: Desmoid-Type Fibromatosis in WHO Classification of Tumors of Soft Tissue and Bone. 2013: 72-73
- 3 Phillips SR, A'Hern R, Thomas JM. Aggressive fibromatosis of the abdominal wall, limbs and limb girdles. Br J Surg 2004; 91 (12) 1624-1629
- 4 Tsagozis P, Stevenson JD, Grimer R, Carter S. Outcome of surgery for primary and recurrent desmoid-type fibromatosis. A retrospective case series of 174 patients. Ann Med Surg (Lond) 2017; 17: 14-19
- 5 Arshad AR, Normala B. Surgical management of large desmoid tumour of the anterior abdominal wall. Asian J Surg 2008; 31 (02) 90-95
- 6 Couto Netto SD, Teixeira Jr F, Menegozzo CAM, Albertini A, Akaishi EH, Utiyama EM. Abdominal wall reconstruction after desmoid type fibromatosis radical resection: case series from a single institution and review of the literature. Int J Surg Case Rep 2017; 33: 167-172
- 7 Mendenhall WM, Zlotecki RA, Morris CG, Hochwald SN, Scarborough MT. Aggressive fibromatosis. Am J Clin Oncol 2005; 28 (02) 211-215
- 8 Macfarlane J. Clinical Reports of the Surgical Practice of the Glasgow Royal Infirmary. D Robertson Glasgow. 1832
- 9 Muller J. Uber den feineran Bau and die For-man der Krankhauten Geschwulste. Berlin G Reimer. 1838
- 10 Lee JC, Thomas JM, Phillips S, Fisher C, Moskovic E. Aggressive fibromatosis: MRI features with pathologic correlation. AJR Am J Roentgenol 2006; 186 (01) 247-254
- 11 Lahrach G. Les tumeurs desmoïdes de la paroi abdominale: quelle stratégie chirurgicale? (A propos de deux cas). 2015. Thèse de doctorat
- 12 Fortunati D, Kaplan J, López Martí J. et al. Desmoid-type fibromatosis in children. Clinical features, treatment response, and long-term follow-up. Medicina (B Aires) 2020; 80 (05) 495-504
- 13 Seidensaal K, Harrabi SB, Weykamp F. et al. Radiotherapy in the treatment of aggressive fibromatosis: experience from a single institution. Radiat Oncol 2020; 15 (01) 143
- 14 Horsley M, Arshad MS, Khan T. Fibromatosis: a review of the risk factors for recurrence and outcomes. Acta Orthop Belg 2020; 86 (S1): 55-60