CC BY-NC-ND 4.0 · Avicenna J Med 2022; 12(02): 073-080
DOI: 10.1055/s-0042-1750730
Original Article

Angina Outcomes in Secondhand Smokers: Results from the National Health and Nutrition Examination Survey 2007–2018

Suzanne Chaar
1   Department of Health Sciences, College of Health Professions and Sciences, Academic Health Sciences Center, University of Central Florida, Orlando, Florida
Jeik Yoon
2   Independent Researcher, Houston, Texas
3   Independent Researcher, Orlando, Florida
José Villalobos
4   Department of Statistics and Data Science, College of Sciences, University of Central Florida, Orlando, Florida
Jeanette Garcia
1   Department of Health Sciences, College of Health Professions and Sciences, Academic Health Sciences Center, University of Central Florida, Orlando, Florida
1   Department of Health Sciences, College of Health Professions and Sciences, Academic Health Sciences Center, University of Central Florida, Orlando, Florida
5   Department of Population Health Sciences, College of Medicine, Academic Health Sciences Center, University of Central Florida, Orlando, Florida
› Author Affiliations
Funding None.


Objective The aim of the study is to examine the relationship between secondhand smoke (SHS) and angina using the National Health and Nutrition Examination Survey database over a 12-year period.

Methods Self-reported smoking status and cotinine levels were used to identify exposure groups (smokers, nonsmokers, and secondhand smokers), and medical history of angina was also collected via a self-report survey. The association between exposure to SHS and angina was analyzed using odd ratios with 95% confidence intervals calculated using two logistic regression models.

Results The study found that when aggregating data from all 12 years, secondhand smokers are 42.9% significantly more likely to report having experienced angina, while smokers were 97.7% significantly more likely to report having angina compared with nonsmokers.

Conclusions This study is the first of its kind to examine data from a national database over a 12-year period to determine an association between SHS and angina outcomes, thus highlighting the importance of reducing SHS exposure to improve cardiovascular health.

Ethical Approval

The study used data from NHANES, which is a publicly available dataset without any identifiable information available for use by the research community. The Institutional Review Board at the University of Central Florida reviewed the study protocol (STUDY00003449) and determined that this study did not meet the federal regulatory definition of research involving humans.

Publication History

Article published online:
03 July 2022

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