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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2022; 32(03): 395-402
DOI: 10.1055/s-0042-1750725
Case Series

Radiological Features of Zollinger–Ellison Syndrome: A Report of Two Cases

Thara Pratap 
1   Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India
,
Muhammed Jasim Abdul Jalal
2   Department of Internal Medicine and Rheumatology, VPS Lakeshore Hospital, Kochi, Kerala, India
,
Dhanya Jacob
1   Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India
,
Pushpa Mahadevan
3   Department of Pathology, VPS Lakeshore Hospital, Kochi, Kerala, India
,
Seethal S. Nair
1   Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India
,
Senthil Raja
4   Department of Nuclear Medicine, VPS Lakeshore Hospital, Kochi, Kerala, India
› Author Affiliations
Funding None.
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Abstract

Hypersecretion of gastrin from duodenal or pancreatic gastrinomas results in a rare clinical entity called Zollinger–Ellison syndrome (ZES). It mostly presents with abdominal pain and diarrhea. ZES may be sporadic or occur in association with multiple endocrine neoplasia type 1. Usually, ZES manifests between 20 and 50 years.

We report two cases of patients who presented with abdominal pain, vomiting, watery diarrhea, and significant weight loss.

Keywords

Zollinger–Ellison syndrome - peptic ulcer - diarrhea - gastrinomas


Publication History

Article published online:
17 August 2022

© 2022. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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