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CC BY 4.0 · World J Nucl Med 2023; 22(01): 022-025
DOI: 10.1055/s-0042-1750401
Case Report

Synchronous Bilateral Multifocal Warthin's Tumor Mimicking Primary Malignancy on 18F-FDG Whole Body PET/CT in a Case of Metastatic Cervical Lymph Nodes from Unknown Primary Malignancy

Shyma Basheer
1   Department of Nuclear Medicine & Molecular Imaging, Amrita Institute of Medical Sciences, Kochi, Kerala, India
,
Alamelu Satish
1   Department of Nuclear Medicine & Molecular Imaging, Amrita Institute of Medical Sciences, Kochi, Kerala, India
,
Archana George Vallonthaiel
1   Department of Nuclear Medicine & Molecular Imaging, Amrita Institute of Medical Sciences, Kochi, Kerala, India
,
Manjit Sarma
1   Department of Nuclear Medicine & Molecular Imaging, Amrita Institute of Medical Sciences, Kochi, Kerala, India
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Abstract

Warthin's tumor is a benign and frequently encountered salivary gland neoplasm. Bilaterality and multifocality are rare in Warthin's tumor. Synchronous cervical lymph nodal metastasis with unknown primary in a case of Warthin's tumor can raise a suspicion of primary malignancy of the parotid gland. We present a case of bilateral multifocal Warthin's tumor with synchronous squamous cell carcinoma metastasis to the cervical lymph node. 18F-fluorodeoxyglucose whole body positron emission tomography/computed tomography imaging showed hypermetabolic bilateral multifocal parotid lesions and metastatic cervical lymph node with unknown primary malignancy.

Keywords

Warthin's tumor - metastatic cervical lymph node with unknown origin - 18F-FDG - PET/CT


Publication History

Article published online:
09 September 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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  • References

  • 1 Chulam TC, Noronha Francisco AL, Goncalves Filho J, Pinto Alves CA, Kowalski LP. Warthin's tumour of the parotid gland: our experience. Acta Otorhinolaryngol Ital 2013; 33 (06) 393-397
    PubMedGoogle Scholar
  • 2 Nguyen VX, Nguyen BD, Ram PC. Bilateral and multifocal Warthin's tumors of parotid glands: PET/CT imaging. Clin Nucl Med 2012; 37 (02) 175-177
    CrossrefPubMedGoogle Scholar
  • 3 Karapolat I, Kumanlıoğlu K. Impact of FDG-PET/CT for the detection of unknown primary tumours in patients with cervical lymph node metastases. Mol Imaging Radionucl Ther 2012; 21 (02) 63-68
    CrossrefPubMedGoogle Scholar
  • 4 Qaseem A, Usman N, Jayaraj JS, Janapala RN, Kashif T. Cancer of unknown primary: a review on clinical guidelines in the development and targeted management of patients with the unknown primary site. Cureus 2019; 11 (09) e5552 DOI: 10.7759/cureus.5552.
    CrossrefPubMedGoogle Scholar
  • 5 Rassekh CH, Cost JL, Hogg JP, Hurst MK, Marano GD, Ducatman BS. Positron emission tomography in Warthin's tumor mimicking malignancy impacts the evaluation of head and neck patients. Am J Otolaryngol 2015; 36 (02) 259-263
    CrossrefPubMedGoogle Scholar
  • 6 Dua SG, Purandare NC, Shah S, Rangarajan V. Bilateral synchronous and multifocal Warthin's tumor mimicking metastases from lung cancer: A rare cause of false positive flourodeoxy glucose positron emission tomography/computed tomography. Indian J Nucl Med 2012; 27 (02) 139-140
    CrossrefPubMedGoogle Scholar
  • 7 Akhtar K, Ray PS, Sherwani R, Siddiqui S. Primary squamous cell carcinoma of the parotid gland: a rare entity. BMJ Case Rep 2013; 2013: bcr2013009467 DOI: 10.1136/bcr-2013-009467.
    Google Scholar