J Neurol Surg A Cent Eur Neurosurg 2023; 84(01): 65-68
DOI: 10.1055/s-0042-1750176
Original Article

Postoperative Quality of Life in Patients with Pyogenic Spondylodiscitis

Tammam Abboud
1   Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany
,
Magdalena Krolikowska-Fluori
1   Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany
,
Patrick Melich
1   Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany
,
Veit Rohde
1   Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany
,
1   Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany
› Author Affiliations

Abstract

Background Pyogenic spondylodiskitis affects a fragile patient population frequently fraught with severe comorbidities. Data on long-term outcomes, especially for patients undergoing surgery, are scarce. The aim of this study was to assess the long-term quality of life after surgical instrumentation.

Methods Data of 218 patients who were treated for spondylodiskitis at our institution between January 2008 and July 2017 were reviewed. In-hospital death and mortality rates at 1 year and follow-up were assessed. A survey was conducted using the following questionnaires: Oswestry Disability Index (ODI), Short Form Work Ability Index (SF-WAI), 36-Item Short Form Health Survey (SF-36), and Short Form McGill Pain Questionnaire (SF-MPQ). We investigated the correlation between the assessed variables and clinical data including patient age, comorbidity score at admission, number of operated levels, corpectomy, and length of hospital stay.

Results In-hospital mortality rate was 1.8% and 1-year mortality rate was 5.5%. At the final follow-up (mean 7 ± 6 years), the mortality rate was 45.4%. Seventy-four patients were lost to follow-up or refused to participate in the study. Forty-four patients responded to the survey and had a mean age of 73 years and mean follow-up of 7 ± 2 years. In the ODI questionnaire, disability grades were classified as minimal (23%), moderate (21%), severe (19%), complete (33%), and bed bound (4%). We found a significant correlation between inability to return to work and severe disability on ODI (p < 0.001), as well as a low score on any component of the SF-36 (p < 0.05).

Conclusion Despite low in-hospital and 1-year mortality rates, patients with surgically treated pyogenic spondylodiskitis are prone to long-term limitation in all domains of quality of life, especially in physical health and work ability.



Publication History

Received: 11 October 2021

Accepted: 10 April 2022

Article published online:
25 July 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Hadjipavlou AG, Mader JT, Necessary JT, Muffoletto AJ. Hematogenous pyogenic spinal infections and their surgical management. Spine 2000; 25 (13) 1668-1679
  • 2 Bettini N, Girardo M, Dema E, Cervellati S. Evaluation of conservative treatment of non specific spondylodiscitis. Eur Spine J 2009; 18 (Suppl. 01) 143-150
  • 3 Valancius K, Hansen ES, Høy K, Helmig P, Niedermann B, Bünger C. Failure modes in conservative and surgical management of infectious spondylodiscitis. Eur Spine J 2013; 22 (08) 1837-1844
  • 4 Guerado E, Cerván AM. Surgical treatment of spondylodiscitis. An update. Int Orthop 2012; 36 (02) 413-420
  • 5 Mann S, Schütze M, Sola S, Piek J. Nonspecific pyogenic spondylodiscitis: clinical manifestations, surgical treatment, and outcome in 24 patients. Neurosurg Focus 2004; 17 (06) E3
  • 6 Shiban E, Janssen I, Wostrack M. et al. A retrospective study of 113 consecutive cases of surgically treated spondylodiscitis patients. A single-center experience. Acta Neurochir (Wien) 2014; 156 (06) 1189-1196
  • 7 Ware J, Snoww K, Ma K, Bg G. SF-36 Health Survey: Manual and Interpretation Guide. Boston, MA: Health Institute, New England Medical Center; 1993
  • 8 Fairbank JC, Pynsent PB. The Oswestry Disability Index. Spine 2000; 25 (22) 2940-2952 , discussion 2952
  • 9 Schouten LS, Bültmann U, Heymans MW, Joling CI, Twisk JWR, Roelen CAM. Shortened version of the work ability index to identify workers at risk of long-term sickness absence. Eur J Public Health 2016; 26 (02) 301-305
  • 10 Bullinger MKI. SF-36 Fragebogen zum Gesundheitszustand. Z Klin Psychol Psychother 1998; 28: 143-145
  • 11 Akiyama T, Chikuda H, Yasunaga H, Horiguchi H, Fushimi K, Saita K. Incidence and risk factors for mortality of vertebral osteomyelitis: a retrospective analysis using the Japanese diagnosis procedure combination database. BMJ Open 2013; 3 (03) e002412
  • 12 Courjon J, Lemaignen A, Ghout I. et al; DTS (Duration of Treatment for Spondylodiscitis) Study Group. Pyogenic vertebral osteomyelitis of the elderly: characteristics and outcomes. PLoS One 2017; 12 (12) e0188470
  • 13 Segreto FA, Beyer GA, Grieco P. et al. Vertebral osteomyelitis: a comparison of associated outcomes in early versus delayed surgical treatment. Int J Spine Surg 2018; 12 (06) 703-712
  • 14 Sobottke R, Röllinghoff M, Zarghooni K. et al. Spondylodiscitis in the elderly patient: clinical mid-term results and quality of life. Arch Orthop Trauma Surg 2010; 130 (09) 1083-1091
  • 15 Woertgen C, Rothoerl RD, Englert C, Neumann C. Pyogenic spinal infections and outcome according to the 36-item short form health survey. J Neurosurg Spine 2006; 4 (06) 441-446