CC BY-NC-ND 4.0 · Indian Journal of Neurosurgery 2023; 12(01): 064-070
DOI: 10.1055/s-0042-1749141
Original Article

Pathological Spectrum of Vascular Malformations of the Central Nervous System: A Single Institution Experience of a Decade

Shrithi Karanth*
1   Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bengaluru, India
,
Shilpa Rao*
1   Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bengaluru, India
,
Amey Savardekar
2   Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India
,
Aravind HR
3   Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Bangaluru, India
,
Nupur Pruthi
2   Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India
,
Arimapamagan Arivazhagan
2   Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India
,
Dhananjaya I. Bhat
2   Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India
,
Dwarakanath Srinivas
2   Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India
,
Bhagvatula Indira Devi
2   Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India
,
Sampath Somanna
2   Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India
,
1   Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bengaluru, India
› Author Affiliations

Abstract

Background Vascular malformations (VMs) of the central nervous system comprise a variety of lesions that could affect the arteries, veins, or capillaries.

Materials and Methods We analyzed the histopathological features of all the VMs diagnosed at our centre over a decade.

Results Intracranial VM included arteriovenous malformation (AVM) (53%), cerebral cavernous malformations (CCMs) (45%), capillary telangiectasia (2%), venous angioma (0.5%), and arteriovenous fistula (AVF) (0.5%). In spinal VMs, capillary telangiectasia (40%) were the most common, followed by cavernomas (34%), AVF (16%), and AVMs and venous angiomas (5%). Clinical presentation varied from focal deficit to features of raised intracranial tension.

Conclusion Imaging and histopathology plays an important role in the diagnosis and management of VMs. Histopathological examination is essential for characterization of the VMs, which influences the prognosis.

Note

The study is a retrospective review of histopathological and clinical data from case records. Consent to use the tissue for research purpose was taken at the time of surgery.


* Both have contributed equally.




Publication History

Article published online:
28 June 2022

© 2022. Neurological Surgeons' Society of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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