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DOI: 10.1055/s-0042-1748837
A Clinical Risk Analysis of Postoperative Nausea and Vomiting After Colorectal Cancer Surgery
Authors
Funding None to declare.
Abstract
Objective Postoperative nausea and vomiting (PONV) is a frequent complication following colorectal surgery. The present study investigated the risk factors for PONV after colorectal cancer surgery.
Methods A retrospective study of 204 patients who underwent surgery for colorectal cancer was conducted. Univariate and multivariate analyses were performed to determine the clinicopathological factors associated with PONV.
Results The overall incidence of postoperative nausea (PON) and postoperative vomit (POV) was 26.5% (54/204), and 12.3% (25/204), respectively. The univariate analysis showed that female gender (p < 0.001), no current alcohol drinking habit (p = 0.003), and no stoma creation (p = 0.023) were associated with PON. Postoperative vomit was significantly correlated with female gender (p = 0.009), high body mass index (p = 0.017), and right-sided colon cancer (p = 0.001). The multivariate logistic regression analysis revealed that female gender (odds ratio [OR]: 4.225; 95% confidence interval [CI]: 2.170–8.226; p < 0.001) was an independent risk factor for PON. A high body mass index (OR: 1.148; 95%CI: 1.018–1.295; p = 0.025), and right-sided colon cancer (OR: 3.337; 95%CI: 1.287–8.652; p = 0.013) were independent risk factors for POV.
Conclusion Our findings suggest that female gender for PON and a high body mass index and right-sided colon cancer for POV are risk factors after colorectal cancer surgery. An assessment using these factors might be helpful for predicting PONV.
Ethics Approval
The medical ethics committee of Saga Medical Center Koseikan reviewed and approved the present study design (permission number: 21-03-01-05).
Consent to Participate
All patients and their families were informed about the surgical procedure and provided their written consent. Broad consent for this study was obtained.
Consent for Publication
Broad consent was obtained for the present study.
Availability of Data and Material
The data sets generated during the present study are available from the corresponding author on reasonable request.
Author Contributions
Hiraki M., Koga M. and Miura D. designed the present study. Hiraki M., Tanaka T., Koga M., Miura D., Sato H., Mitsumizo S., and Kitahara K. treated the patients. Hiraki M. and Sadashima E. (specialist in statistics) analyzed the data. Hiraki M., Tanaka T., Koga M. and Miura D. interpreted the results and wrote the manuscript.
Publikationsverlauf
Eingereicht: 07. Dezember 2021
Angenommen: 03. März 2022
Artikel online veröffentlicht:
21. Juli 2022
© 2022. Sociedade Brasileira de Coloproctologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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