Prostate Artery Embolization in Patients above Eighty Years Old: Clinical Efficacy and SafetyFunding The researcher's (Hossam Saro) clinical and research time at Guy's and St Thomas' Hospitals was funded by the Mission's Office, Ministry of Higher Education, Egypt.
Objectives Prostate artery embolization (PAE) has been established as an effective treatment option for benign prostate hyperplasia or hematuria of prostatic origin. We aim to confirm the effectiveness and safety of PAE in elderly patients aged ≥ 80 years old.
Materials and Methods Between January 2014 and August 2020, PAE was attempted on 54 elderly patients with lower urinary tract symptoms (LUTS) or prostatic hematuria who were unfit for surgical treatment or opted for PAE. Outcome parameters (International Prostate Symptom Score [IPSS], quality of life [QoL] score, International Index of Erectile Function score (IIEF), maximal urinary flow rate, postvoid residual, and prostate volume) were collected and analyzed at baseline, 6 months, 1, 2, and 3 years.
Results The mean patient age was 85.29 years (range: 80–98). Technical success was achieved in 50 patients (92.6%). Mean IPSS improved from 18 at baseline to 7.7, 8.5, 8.6, and 9.1 at 6 months, 1, 2, and 3 years. Mean QoL improved from 4.9 at baseline to 2.8, 1.7, and 1.5 at 6 months, 1, and 2 years. Mean prostate volume reduced from a baseline of 152.7 to 123.5 mL within 6 months and 120.5 mL after 7 months of PAE. Urinary catheter removal was successful in 13 out of 19 patients with urinary retention. PAE succeeded in stopping bleeding in 16 out of 17 patients with prostate-induced hematuria.
Conclusion PAE is a feasible low-risk treatment for LUTS with or without urinary retention or prostatic hematuria in elderly patients.
Keywordsbenign prostate hyperplasia - urinary retention - prostate-induced hematuria - prostate artery embolization - lower urinary tract symptoms
The study was conducted following the approval of the research ethics board at Guy's and St Thomas' Hospitals, London, United Kingdom.
Informed consent was obtained from all participants in the study, and all procedures were approved by the research ethics board.
Artikel online veröffentlicht:
14. Juni 2022
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