Open Access
CC BY-NC-ND 4.0 · Laryngorhinootologie 2022; 101(S 02): S243-S244
DOI: 10.1055/s-0042-1746898
Abstracts | DGHNOKHC
Otology / Neurootology / Audiology: Neurootology / Vertigo

Regenerative capacity in acute vestibular neuropathia in the short-term interval

Authors

  • Maximilian von Bernstorff

    1   Klinik für Hals-Nasen-Ohrenheilkunde, Campus Benjamin Franklin, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Deutschland Berlin

  • Erdi Hoxhallari

    1   Klinik für Hals-Nasen-Ohrenheilkunde, Campus Benjamin Franklin, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Deutschland Berlin

  • Theresa Obermüller

    1   Klinik für Hals-Nasen-Ohrenheilkunde, Campus Benjamin Franklin, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Deutschland Berlin

  • Uwe Schönfeld

    1   Klinik für Hals-Nasen-Ohrenheilkunde, Campus Benjamin Franklin, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Deutschland Berlin

  • VeitMaria Hofmann

    1   Klinik für Hals-Nasen-Ohrenheilkunde, Campus Benjamin Franklin, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Deutschland Berlin

  • Anett Pudszuhn

    1   Klinik für Hals-Nasen-Ohrenheilkunde, Campus Benjamin Franklin, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Deutschland Berlin
Further Information
Also available at
 

Background 

Vertigo compensation of acute vestibular neuropathia (aVN) varies widely among individuals. The regenerative capacity of the different sensors is unclear. In this study, clinical and instrumental examination of all labyrinth substructures was performed in a short-term interval.

Methods 

This prospective study examined 39 patients (22 ♂, 17 ♀, age: ∅55±18 years) with initial aVN and at after five weeks on average. Medical history, clinical examination and instrumental otoneurological diagnostics (caloric test (CT), video head thrust test of all semicircular canals (vHIT), rotatory pendulum test (RPT), cervical/ocular vestibular evoked myogenic potentials (c/oVEMPs)) were performed.

Results 

Subjective partial improvement of vertigo was reported in 87% of the cases. On instrumental control a spontaneous nystagmus was still detectable in 50% and vestibulospinal examination remained abnormal in 54%. The horizontal canal showed a significant recovery in CT, but excitability was symmetrical in only 15.4% of the cases. The vKIT was unremarkable in 26.3% of the cases in the control. The RPT was compensated in 47%. The cVEMPs and the oVEMPS were reproducible in 24% of cases again.

Discussion 

Within the first weeks after aVN, there is subjectively a symptom reduction. However, it is always necessary to distinguish between individually different regeneration of the semicircular canals, the otolith organs and central compensation. A clinical examination alone is not sufficient to identify residual dysfunction after aVN. The range of compensation requires differentiated otoneurological controls and rehabilitation individually adapted to the receptor deficit.



Publication History

Article published online:
24 May 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Georg Thieme Verlag
Rüdigerstraße 14, 70469 Stuttgart,Germany