Nasopharyngeal tumors in adults – a retrospective analysis over 10 years

Introduction Adenoid Hyperplasia is especially in childhood a common diagnosis in otorhinolaryngology. Histological investigation of nasopharyngeal tumors in adults is due to a higher rate of malignancies a rational diagnostic procedure. The aim of our study was to analyze data of histological investigated cases.

Material and Methods 687 patients with histologically investigated nasopharyngeal tumors were analyzed. A retrospective analysis of all patients was performed over a period of ten years (2011 -2020). Descriptive and statistical analysis was performed.

Results Within 687 cases 107 cases were malign and 580 benign. The most frequent diagnosis in our analysis was adenoid hyperplasia. Within malignant cases, lymphoepithelial cancer, squamous cell carcinoma, and lymphoma were the most common. Whereas in benign cases gender distribution was equal, malignancies occurred more often in male patients. Patients with benign tumors showed a statistically significant lower age than malignant cases (benign: Median age 42 years; malignant: Median age 58 years; p < 0.0001). The initial clinical diagnosis was correct in most cases.

Conclusion With a low complication rate, a non-negligible rate of malignant diagnoses was found after nasopharyngoscopy was performed in adult patients. In case of an unclear mass in the nasopharynx, an indication for histological workup should be given.

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Artikel online veröffentlicht:
24. Mai 2022