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CC BY-NC-ND 4.0 · Arch Plast Surg 2022; 49(03): 339-345
DOI: 10.1055/s-0042-1744419
Breast/Trunk
Original Article

Prolonged Opioid Use Among Opioid-Naive Women Undergoing Breast Reconstructive Surgery

Ankhita R. Samuel 
1   Department of Plastic Surgery, University of Virginia, Charlottesville, Virginia
,
Laura Fuhr
1   Department of Plastic Surgery, University of Virginia, Charlottesville, Virginia
,
Brent R. DeGeorge Jr
1   Department of Plastic Surgery, University of Virginia, Charlottesville, Virginia
,
Jonathan Black
1   Department of Plastic Surgery, University of Virginia, Charlottesville, Virginia
,
Christopher Campbell
1   Department of Plastic Surgery, University of Virginia, Charlottesville, Virginia
,
John T. Stranix
1   Department of Plastic Surgery, University of Virginia, Charlottesville, Virginia
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Abstract

Background Patients that undergo mastectomy for breast cancer with reconstruction may be prone to prolonged opioid use. As risk factors are not well-established, this article sought to better understand the risk factors that may be associated with this.

Methods Patients that underwent breast reconstruction between 2010 and 2018 were identified in PearlDiver, a national insurance claims database. Patient demographics and comorbidities were elucidated, and various complications were then identified. Descriptive statistics as well as a multivariate analysis was used to evaluate the association of risk factors and complications.

Results Breast reconstruction patients of 24,765 were identified from this database. Obesity, tobacco use, benzodiazepine use, and anticonvulsant use were all associated with prolonged opioid prescriptions greater than 90 days after both alloplastic and autologous reconstruction.

Conclusion Prolonged opioid use continues to remain a topic of concern, and particularly in cancer patients that undergo breast reconstruction. Providers should be aware of potential risk factors for this to reduce this chance following breast reconstruction surgery.

Keywords

prolonged opioid use - breast reconstruction - risk factors

Author Contributions

Conceptualization: A.R.S. and J.T.S. Data curation: A.R.S., J.T.S. Formal analysis: A.R.S., J.T.S. Methodology: J.T.S. Project administration: A.R.S. Visualization: A.R.S. and J.T.S. Writing - original draft: A.R.S. and L.F. Writing - review and editing: L.F., B.R.D.Jr, J.B., C.C., J.S.


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Publication History

Article published online:
27 May 2022

© 2022. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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