Vet Comp Orthop Traumatol 2022; 35(03): 198-204
DOI: 10.1055/s-0042-1744181
Clinical Communication

A New Generation of Osteochondral Autograft Transfer System for the Treatment of Osteochondritis Dissecans of the Femoral Condyle: Clinical Experience in 18 Dogs

1   Clinica Veterinaria Vezzoni, Cremona, Italy
2   Clinica Veterinaria Apuana-Anicura, Marina di Carrara, Italy
Luca Vezzoni
1   Clinica Veterinaria Vezzoni, Cremona, Italy
Aldo Vezzoni
1   Clinica Veterinaria Vezzoni, Cremona, Italy
› Author Affiliations
Funding None.


Objectives The aim of this study was to describe the clinical application and outcome of osteochondral autograft transfer using the COR system (COR; DePuy Synthes, Warsaw, Indiana, United States) for the treatment of osteochondritis dissecans (OCD) of the femoral condyle in dogs.

Methods Medical records of dogs that were treated for OCD of the femoral condyle using the COR system between February 2013 and March 2020 were retrospectively reviewed. The results of pre- and postoperative clinical and radiographic examinations were evaluated.

Results Twenty stifles (18 dogs; 15 lateral and 5 medial femoral condyles) met the inclusion criteria. A single graft transfer was done in six stifle joints and mosaicplasty in 14 (2 grafts in 9/14 stifles; 3 grafts in 5/14 stifles). Proper anatomic reconstruction was confirmed intraoperatively and radiographically in all dogs. There were no major and three minor postoperative complications. At 3 months, 15 of 20 stifles (14 of 18 dogs) had no lameness or radiographic signs of inflammation. At 6 months, 12 of 13 dogs had no lameness or discomfort, and four of 13 stifles had radiographic evidence of moderate osteoarthritis.

Clinical Significance Treatment of OCD of the femoral condyle using the COR system is feasible in dogs, with low complications and provides a satisfactory short-term outcome.

Authors' Contributions

All authors contributed to conception of the study, study design, acquisition of data, data analysis and interpretation. F.C. primarily drafted, revised and approved the submitted manuscript. L.V. and A.V. performed the surgeries, revised and approved the submitted manuscript.

Supplementary Material

Publication History

Received: 18 April 2021

Accepted: 04 February 2022

Article published online:
10 March 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

  • References

  • 1 Ekman S, Carlson CS. The pathophysiology of osteochondrosis. Vet Clin North Am Small Anim Pract 1998; 28 (01) 17-32
  • 2 Harari J. Osteochondrosis of the femur. Vet Clin North Am Small Anim Pract 1998; 28 (01) 87-94
  • 3 Montgomery RD, Henderson RA, Milton JL. et al. Osteochondritis dissecans of the canine stifle. Compend Contin Educ Pract Vet 1989; 11: 1199-1205
  • 4 Cook JL, Hudson CC, Kuroki K. Autogenous osteochondral grafting for treatment of stifle osteochondrosis in dogs. Vet Surg 2008; 37 (04) 311-321
  • 5 Fitzpatrick N, Yeadon R, van Terheijden C, Smith TJ. Osteochondral autograft transfer for the treatment of osteochondritis dissecans of the medial femoral condyle in dogs. Vet Comp Orthop Traumatol 2012; 25 (02) 135-143
  • 6 Kulendra E, Lee K, Schoeniger S, Moores AP. Osteochondritis dissecans-like lesion of the intercondylar fossa of the femur in a dog. Vet Comp Orthop Traumatol 2008; 21 (02) 152-155
  • 7 Gudas R, Kalesinskas RJ, Kimtys V. et al. A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes. Arthroscopy 2005; 21 (09) 1066-1075
  • 8 Pareek A, Reardon PJ, Macalena JA. et al. Osteochondral autograft transfer versus microfracture in the knee: a meta-analysis of prospective comparative studies at midterm. Arthroscopy 2016; 32 (10) 2118-2130
  • 9 Robinson PG, Williamson T, Murray IR, Al-Hourani K, White TO. Sporting participation following the operative management of chondral defects of the knee at mid-term follow up: a systematic review and meta-analysis. J Exp Orthop 2020; 7 (01) 76-79
  • 10 Palierne S, Bilmont A, Raymond-Letron I, Autefage A. A case of stifle osteochondrosis treated by osteochondral autogenous grafting. One month morphological follow-up. Vet Comp Orthop Traumatol 2010; 23 (03) 190-195
  • 11 Fitzpatrick N, Yeadon R, Smith TJ. Early clinical experience with osteochondral autograft transfer for treatment of osteochondritis dissecans of the medial humeral condyle in dogs. Vet Surg 2009; 38 (02) 246-260
  • 12 Fitzpatrick N, van Terheijden C, Yeadon R, Smith TJ. Osteochondral autograft transfer for treatment of osteochondritis dissecans of the caudocentral humeral head in dogs. Vet Surg 2010; 39 (08) 925-935
  • 13 Innes JF, Costello M, Barr FJ, Rudorf H, Barr AR. Radiographic progression of osteoarthritis of the canine stifle joint: a prospective study. Vet Radiol Ultrasound 2004; 45 (02) 143-148
  • 14 Crist BD, Stoker AM, Pfeiffer FM. et al. Optimising femoral-head osteochondral allograft transplantation in a preclinical model. J Orthop Translat 2015; 5: 48-56
  • 15 Andrade R, Vasta S, Pereira R. et al. Knee donor-site morbidity after mosaicplasty - a systematic review. J Exp Orthop 2016; 3 (01) 31-36
  • 16 Böttcher P, Zeissler M, Maierl J, Grevel V, Oechtering G. Mapping of split-line pattern and cartilage thickness of selected donor and recipient sites for autologous osteochondral transplantation in the canine stifle joint. Vet Surg 2009; 38 (06) 696-704
  • 17 McKee WM, Cook JL. The stifle. In: Houlton JEF, Cook JL, Innes JF. et al, eds. Manual of Canine and Feline Musculoskeletal Disorders. Ed II. Gloucester, UK: British Small Animal Veterinary Association; 2006: 350-395