CC BY 4.0 · Aorta (Stamford) 2022; 10(01): 026-031
DOI: 10.1055/s-0042-1744136
Original Research Article

Direct Innominate Artery Cannulation versus Side Graft for Selective Antegrade Cerebral Perfusion during Aortic Hemiarch Replacement

1   Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado
,
Cenea Kemp
1   Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado
,
Christian V. Ghincea
1   Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado
,
1   Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado
,
Yuki Ikeno
1   Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado
,
1   Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado
,
T. Brett Reece
1   Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado
› Author Affiliations
Funding None.

Abstract

Background Selective antegrade cerebral perfusion (SACP) has become our preferred method for cerebral protection during open arch cases. While the initial approach involved sewing a graft to the innominate artery as the arterial cannulation site, our access strategy has since evolved to central aortic cannulation with use of a percutaneous cannula in the innominate for SACP. We hypothesized that SACP delivered via direct innominate cannulation using a 12- or 14-Fr cannula results in equivalent outcomes to cases utilizing a side graft.

Methods This was a single-center, retrospective analysis of 211 adult patients who underwent elective hemiarch replacement using hypothermic circulatory arrest with SACP via the innominate artery between 2012 and 2020. Urgent and emergent cases were excluded.

Results A side graft sutured to the innominate was utilized in 81% (n = 171) of patients, while direct innominate artery cannulation was performed in 19% (n = 40) of patients. Baseline patient characteristics were similar between groups aside from a higher baseline creatinine in the direct cannulation group (1.3 vs. 0.9, p = 0.032). Patients undergoing direct cannulation demonstrated shorter cardiopulmonary bypass time (132.7 vs. 154.9 minutes, p = 0.020) and shorter circulatory arrest time (8.1 vs. 10.9 minutes, p = 0.004). Nadir bladder temperature did not significantly differ between groups (27.2°C for side graft vs. 27.6°C for direct cannulation, p = 0.088). There were no significant differences in postoperative outcomes.

Conclusion Direct cannulation of the innominate artery with a 12- or 14-Fr cannula for SACP during hemiarch replacement is a safe alternative to using a sutured side graft. While cardiopulmonary bypass and circulatory arrest times appear improved, this is likely attributable to accumulation of experience and proficiency in technique. However, direct innominate artery cannulation may facilitate quicker completion of these procedures by eliminating the time necessary to suture a graft to the innominate artery.



Publication History

Received: 30 April 2021

Accepted: 03 September 2021

Article published online:
31 May 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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  • References

  • 1 Czerny M, Fleck T, Zimpfer D. et al. Risk factors of mortality and permanent neurologic injury in patients undergoing ascending aortic and arch repair. J Thorac Cardiovasc Surg 2003; 126 (05) 1296-1301
  • 2 Khaladj N, Shrestha M, Meck S. et al. Hypothermic circulatory arrest with selective antegrade cerebral perfusion in ascending aortic and aortic arch surgery: a risk factor analysis for adverse outcome in 501 patients. J Thorac Cardiovasc Surg 2008; 135 (04) 908-914
  • 3 Leshnower BG, Myung RJ, Chen EP. Aortic arch surgery using moderate hypothermia and unilateral selective antegrade cerebral perfusion. Ann Cardiothorac Surg 2013; 2 (03) 288-295
  • 4 Tsai JY, Pan W, Lemaire SA. et al. Moderate hypothermia during aortic arch surgery is associated with reduced risk of early mortality. J Thorac Cardiovasc Surg 2013; 146 (03) 662-667
  • 5 Vallabhajosyula P, Jassar AS, Menon RS. et al. Moderate versus deep hypothermic circulatory arrest for elective aortic transverse hemiarch reconstruction. Ann Thorac Surg 2015; 99 (05) 1511-1517
  • 6 Eldeiry M, Ghincea C, Aftab M, Cleveland JC, Fullerton D, Reece TB. Innominate versus axillary artery cannulation for the hemiarch repair. J Surg Res 2018; 232: 234-239
  • 7 Preventza O, Bakaeen FG, Stephens EH, Trocciola SM, de la Cruz KI, Coselli JS. Innominate artery cannulation: an alternative to femoral or axillary cannulation for arterial inflow in proximal aortic surgery. J Thorac Cardiovasc Surg 2013; 145 (3, Suppl): S191-S196
  • 8 Garg V, Tsirigotis DN, Dickson J. et al. Direct innominate artery cannulation for selective antegrade cerebral perfusion during deep hypothermic circulatory arrest in aortic surgery. J Thorac Cardiovasc Surg 2014; 148 (06) 2920-2924
  • 9 Ji S, Yang J, Ye X, Wang X. Brain protection by using innominate artery cannulation during aortic arch surgery. Ann Thorac Surg 2008; 86 (03) 1030-1032
  • 10 Mault JR, Ohtake S, Klingensmith ME, Heinle JS, Greeley WJ, Ungerleider RM. Cerebral metabolism and circulatory arrest: effects of duration and strategies for protection. Ann Thorac Surg 1993; 55 (01) 57-63 , discussion 63–64
  • 11 Minatoya K, Ogino H, Matsuda H. et al. Evolving selective cerebral perfusion for aortic arch replacement: high flow rate with moderate hypothermic circulatory arrest. Ann Thorac Surg 2008; 86 (06) 1827-1831
  • 12 Friess J, Beeler M, Heinisch PP, Jenni H, Schoenhoff F, Erdoes G. A low flow rate for selective antegrade cerebral perfusion is sufficient to reach baseline tissue oxygenation of the brain during hypothermic circulatory arrest. J Cardiothorac Vasc Anesth 2019; 33: S122-S123
  • 13 Swain JA, McDonald Jr TJ, Griffith PK, Balaban RS, Clark RE, Ceckler T. Low-flow hypothermic cardiopulmonary bypass protects the brain. J Thorac Cardiovasc Surg 1991; 102 (01) 76-83 , discussion 83–84
  • 14 Huang FJ, Wu Q, Ren CW. et al. Cannulation of the innominate artery with a side graft in arch surgery. Ann Thorac Surg 2010; 89 (03) 800-803
  • 15 Jassar AS, Vallabhajosyula P, Bavaria JE. et al. Direct innominate artery cannulation: an alternate technique for antegrade cerebral perfusion during aortic hemiarch reconstruction. J Thorac Cardiovasc Surg 2016; 151 (04) 1073-1078
  • 16 Payabyab EC, Hemli JM, Mattia A. et al. The use of innominate artery cannulation for antegrade cerebral perfusion in aortic dissection. J Cardiothorac Surg 2020; 15 (01) 205
  • 17 Strauch JT, Spielvogel D, Lauten A. et al. Axillary artery cannulation: routine use in ascending aorta and aortic arch replacement. Ann Thorac Surg 2004; 78 (01) 103-108 , discussion 103–108
  • 18 Etz CD, Plestis KA, Kari FA. et al. Axillary cannulation significantly improves survival and neurologic outcome after atherosclerotic aneurysm repair of the aortic root and ascending aorta. Ann Thorac Surg 2008; 86 (02) 441-446 , discussion 446–447
  • 19 Sabik JF, Lytle BW, McCarthy PM, Cosgrove DM. Axillary artery: an alternative site of arterial cannulation for patients with extensive aortic and peripheral vascular disease. J Thorac Cardiovasc Surg 1995; 109 (05) 885-890 , discussion 890–891
  • 20 Schachner T, Nagiller J, Zimmer A, Laufer G, Bonatti J. Technical problems and complications of axillary artery cannulation. Eur J Cardiothorac Surg 2005; 27 (04) 634-637
  • 21 Banbury MK, Cosgrove III DM. Arterial cannulation of the innominate artery. Ann Thorac Surg 2000; 69 (03) 957
  • 22 Di Eusanio M, Quarti A, Pierri MD, Di Eusanio G. Cannulation of the brachiocephalic trunk during surgery of the thoracic aorta: a simplified technique for antegrade cerebral perfusion. Eur J Cardiothorac Surg 2004; 26 (04) 831-833
  • 23 Preventza O, Garcia A, Tuluca A. et al. Innominate artery cannulation for proximal aortic surgery: outcomes and neurological events in 263 patients. Eur J Cardiothorac Surg 2015; 48 (06) 937-942 , discussion 942
  • 24 Hokenek AF, Kinoglu B, Gursoy M, Sirin G, Gulcan F. Direct innominate artery cannulation in surgery for annuloaortic ectasia. J Card Surg 2013; 28 (05) 550-553
  • 25 Kashani A, Doyle M, Horton M. Direct innominate artery cannulation as a sole systemic and cerebral perfusion technique in aortic surgery. Heart Lung Circ 2019; 28 (04) e67-e70