PDF herunterladen
The Journal of Hip Surgery 2022; 06(02): 058-062
DOI: 10.1055/s-0042-1744133
Original Article

Nicotine Dependence and Incident Hip Replacement Surgery in Individuals with Type 2 Diabetes Mellitus, TRINET-X, 2021

R. Constance Wiener 
1   Department of Dental Practice and Rural Health, Health Sciences Addition, West Virginia University, Morgantown, West Virginia
,
Melissa Suann Gaydos
2   Department of Dental Hygiene, Health Sciences Center North, West Virginia University, Morgantown, West Virginia
,
Jill Cochran
3   Division of Clinical Sciences, West Virginia School of Osteopathic Medicine, Lewisburg, West Virginia
,
Susan Morgan
4   Department of Periodontics, West Virginia University, Morgantown, West Virginia
› Institutsangaben Funding Research reported in this publication was supported by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number 5U54GM104942-04. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
› Weitere Informationen
   Lizenzen und Reprints

Abstract

The purpose of this research is to examine the association between nicotine dependence (yes, no) and hip replacement (yes, no) among people with type 2 diabetes mellitus (T2DM). Data were obtained through the TRINET-X data depository of 18 years or older patients with T2DM and nicotine dependence history. Then, the incidence of hip replacement surgery was determined. Propensity score matching (PSM) was used to determine the risk of hip replacement surgery. After PSM, the risk ratio of hip replacement surgery among people with T2DM was 1.45 (95% confidence interval: 1.45, 1.57; p < 0.0001) for those who had nicotine dependence versus those who did not. Nicotine dependence among people with T2DM was identified as a risk factor for future hip replacement need. Patients who have nicotine dependence should be cautioned about this potential risk.

Keywords

hip replacement - type 2 diabetes mellitus - nicotine dependence

Note

Authors have followed the guidelines of the International Committee of Medical Journal Editors in which they have substantial contributions to (1) conception and design, or acquisition of data or analysis and interpretation of data; (2) drafting the article or revising it critically for important intellectual content; and (3) final approval of the version to be published.


Data Availability

The data used to support the findings of this study are held by TRINET-X, https://trinetx.com.[30]


Ethical Statement

The West Virginia University provided the acknowledgment of this study as meeting the characteristics of a non-human subject research study.




Publikationsverlauf

Eingereicht: 09. Juni 2021

Angenommen: 04. Januar 2022

Artikel online veröffentlicht:
09. März 2022

© 2022. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 

  • References

  • 1 OECD, Organisation for Economic Cooperation and Development. Hip and knee replacement. OECDiLibrary. 2021 . Accessed June 2, 2021 at: https://www.oecd-ilibrary.org/sites/2fc83b9a-en/index.html?itemId=/content/component/2fc83b9a-en
    PubMedGoogle Scholar
  • 2 Maradit Kremers H, Larson DR, Crowson CS. et al. Prevalence of total hip and knee replacement in the United States. J Bone Joint Surg Am 2015; 97 (17) 1386-1397
    CrossrefPubMedGoogle Scholar
  • 3 Steiner C, Andrews R, Barrett M, Weiss A. HCUP Projections: Mobility/Orthopedic Procedures 2003 to 2012. 2012 . HCUP Projections Report # 2012–03. 2012 Sep 20. U.S. Agency for Healthcare Research and Quality. Accessed June 2, 2021 at: http://hcup-us.ahrq.gov/reports/projections/2012-03.pdf
    PubMedGoogle Scholar
  • 4 Basques BA, Bell JA, Sershon RA, Della Valle CJ. The influence of patient gender on morbidity following total hip or total knee arthroplasty. J Arthroplasty 2018; 33 (02) 345-349
    CrossrefPubMedGoogle Scholar
  • 5 Gordon M, Rysinska A, Garland A. et al. Increased long-term cardiovascular risk after total hip arthroplasty: a nationwide cohort study. Medicine (Baltimore) 2016; 95 (06) e2662
    CrossrefPubMedGoogle Scholar
  • 6 Huang CC, Jiang CC, Hsieh CH, Tsai CJ, Chiang H. Local bone quality affects the outcome of prosthetic total knee arthroplasty. J Orthop Res 2016; 34 (02) 240-248
    CrossrefPubMedGoogle Scholar
  • 7 Bottai V, Dell'Osso G, Celli F. et al. Total hip replacement in osteoarthritis: the role of bone metabolism and its complications. Clin Cases Miner Bone Metab 2015; 12 (03) 247-250
    PubMedGoogle Scholar
  • 8 Johnsen MB, Hellevik AI, Småstuen MC. et al. The mediating effect of body mass index on the relationship between smoking and hip or knee replacement due to primary osteoarthritis. A population-based cohort study (the HUNT Study). PLoS One 2017; 12 (12) e0190288
    CrossrefPubMedGoogle Scholar
  • 9 Strozyk D, Gress TM, Breitling LP. Smoking and bone mineral density: comprehensive analyses of the third National Health and Nutrition Examination Survey (NHANES III). Arch Osteoporos 2018; 13 (01) 16
    CrossrefPubMedGoogle Scholar
  • 10 Karlson EW, Mandl LA, Aweh GN, Sangha O, Liang MH, Grodstein F. Total hip replacement due to osteoarthritis: the importance of age, obesity, and other modifiable risk factors. Am J Med 2003; 114 (02) 93-98
    CrossrefPubMedGoogle Scholar
  • 11 Hannan MT, Felson DT, Dawson-Hughes B. et al. Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study. J Bone Miner Res 2000; 15 (04) 710-720
    CrossrefPubMedGoogle Scholar
  • 12 Ward KD, Klesges RC. A meta-analysis of the effects of cigarette smoking on bone mineral density. Calcif Tissue Int 2001; 68 (05) 259-270
    CrossrefPubMedGoogle Scholar
  • 13 Mnatzaganian G, Ryan P, Reid CM, Davidson DC, Hiller JE. Smoking and primary total hip or knee replacement due to osteoarthritis in 54,288 elderly men and women. BMC Musculoskelet Disord 2013; 14: 262
    CrossrefPubMedGoogle Scholar
  • 14 Gullahorn L, Lippiello L, Karpman R. Smoking and osteoarthritis: differential effect of nicotine on human chondrocyte glycosaminoglycan and collagen synthesis. Osteoarthritis Cartilage 2005; 13 (10) 942-943
    CrossrefPubMedGoogle Scholar
  • 15 Dawson LP, Fairley JL, Papandony MC, Hussain SM, Cicuttini FM, Wluka AE. Is abnormal glucose tolerance or diabetes a risk factor for knee, hip, or hand osteoarthritis? A systematic review. Semin Arthritis Rheum 2018; 48 (02) 176-189
    CrossrefPubMedGoogle Scholar
  • 16 Sheu Y, Amati F, Schwartz AV. et al; Osteoporotic Fractures in Men (MrOS) Research Group. Vertebral bone marrow fat, bone mineral density and diabetes: the Osteoporotic Fractures in Men (MrOS) study. Bone 2017; 97: 299-305
    CrossrefPubMedGoogle Scholar
  • 17 Zhu Z, Sheng X, Zhang J, Yao X. Association between type 2 diabetes status and osteoarthritis in adults aged ≥ 50 years. J Orthop Sci 2021; (e-pub ahead of print) DOI: 10.1016/j.jos.2020.12.001.
    CrossrefPubMedGoogle Scholar
  • 18 Khor A, Ma CA, Hong C, Hui LL, Leung YY. Diabetes mellitus is not a risk factor for osteoarthritis. RMD Open 2020; 6 (01) e001030
    CrossrefPubMedGoogle Scholar
  • 19 Krieger N. Epidemiology and the People's Health: Theory and Context. New York, NY: Oxford University Press; 2011
    CrossrefGoogle Scholar
  • 20 Singh S, Khan A. Clinical characteristics and outcomes of coronavirus disease 2019 among patients with preexisting liver disease in the United States: a multicenter research network study. Gastroenterology 2020; 159 (02) 768-771.e3
    CrossrefPubMedGoogle Scholar
  • 21 Singh S, Khan A, Chowdhry M, Bilal M, Kochhar GS, Clarke K. Risk of severe coronavirus disease 2019 in patients with inflammatory bowel disease in the United States: a multicenter research network study. Gastroenterology 2020; 159 (04) 1575-1578.e4
    CrossrefPubMedGoogle Scholar
  • 22 Uzunel E, Lundin H, Wändell P, Salminen H. Association between self-rated health and the risk of hip fracture and mortality in a cohort of older women during a 10-year follow-up. PLoS One 2021; 16 (03) e0247924
    CrossrefPubMedGoogle Scholar
  • 23 Thorin MH, Wihlborg A, Åkesson K, Gerdhem P. Smoking, smoking cessation, and fracture risk in elderly women followed for 10 years. Osteoporos Int 2016; 27 (01) 249-255
    CrossrefPubMedGoogle Scholar
  • 24 Kanis JA, Johnell O, Oden A. et al. Smoking and fracture risk: a meta-analysis. Osteoporos Int 2005; 16 (02) 155-162
    CrossrefPubMedGoogle Scholar
  • 25 Hernigou J, Schuind F. Tobacco and bone fractures: a review of the facts and issues that every orthopaedic surgeon should know. Bone Joint Res 2019; 8 (06) 255-265
    CrossrefPubMedGoogle Scholar
  • 26 Qiu J, Li C, Dong Z, Wang J. Is diabetes mellitus a risk factor for low bone density: a systematic review and meta-analysis. BMC Endocr Disord 2021; 21 (01) 65
    CrossrefPubMedGoogle Scholar
  • 27 Williams MF, London DA, Husni EM, Navaneethan S, Kashyap SR. Type 2 diabetes and osteoarthritis: a systematic review and meta-analysis. J Diabetes Complications 2016; 30 (05) 944-950
    CrossrefPubMedGoogle Scholar
  • 28 Eller-Vainicher C, Cairoli E, Grassi G. et al. Pathophysiology and management of type 2 diabetes mellitus bone fragility. J Diabetes Res 2020; 2020: 7608964
    CrossrefPubMedGoogle Scholar
  • 29 DeGroot J, Verzijl N, Wenting-van Wijk MJ. et al. Accumulation of advanced glycation end products as a molecular mechanism for aging as a risk factor in osteoarthritis. Arthritis Rheum 2004; 50 (04) 1207-1215
    CrossrefPubMedGoogle Scholar
  • 30 [dataset] TriNetX. 2021 . Accessed June 2, 2021 at: https://trinetx.com
    PubMedGoogle Scholar