Abstract
Based on observations at angiography, it was hypothesized that angiomyolipomas (AMLs)
associated with tuberous sclerosis complex (TSC) have a more robust parasitic blood
supply and require more complex embolization involving lower order vessels compared
with the non-TSC patients' AMLs. This was a retrospective review of 71 patients who
underwent angiography and embolization for renal AML at multiple centers within a
single health system. All of the patients with TSC (11/11) were found to have “complex”
tumor vascular supply. Of the patients with sporadic AML, 51/60 (85%) had “simple”
tumor vascular supply. Sporadic cases with a complex tumor blood supply were larger
tumors, with an average size of 11.5 cm. This study supports our hypothesis that AMLs
associated with TSC have more complex tumor vascularity compared with sporadic lesions,
and aims to better prepare interventionalists to deal with the complex cases.
Keywords
AML - tuberous sclerosis - tuberous sclerosis complex - tumor - embolization - complex
tumor vascularity - hemorrhage
