CC BY-NC-ND 4.0 · Yearb Med Inform 2022; 31(01): 203-214
DOI: 10.1055/s-0042-1742519
Section 7: Health Information Exchange
Survey

Transforming Health Data to Actionable Information: Recent Progress and Future Opportunities in Health Information Exchange

Indra Neil Sarkar
1   Brown University, Providence, RI, USA
2   Rhode Island Quality Institute, Providence, RI, USA
› Author Affiliations

Summary

Objectives: Provide a systematic review of literature pertaining to health information exchange (HIE) since 2018. Summarize HIE-associated literature for most frequently occurring topics, as well as within the context of the COVID-19 pandemic and health equity. Finally, provide recommendations for how HIE can advance the vision of a digital healthcare ecosystem.

Methods: A computer program was developed to mediate a literature search of primary literature indexed in MEDLINE that was: (1) indexed with “Health Information Exchange” MeSH descriptor as a major topic; and (2) published between January 2018 and December 2021. Frequency of MeSH descriptors was then used to identify and to rank topics associated with the retrieved literature. COVID-19 literature was identified using the general COVID-19 PubMed Clinical Query filter. Health equity literature was identified using additional MeSH descriptor-based searches. The retrieved literature was then reviewed and summarized.

Results: A total of 256 articles were retrieved and reviewed for this survey. The major thematic areas summarized were: (1) Information Dissemination; (2) Delivery of Health Care; (3) Hospitals; (4) Hospital Emergency Service; (5) COVID-19; (6) Health Disparities; and (7) Computer Security and Confidentiality. A common theme across all areas examined for this survey was the maturity of HIE to support data-driven healthcare delivery. Recommendations were developed based on opportunities identified across the reviewed literature.

Conclusions: HIE is an essential advance in next generation healthcare delivery. The review of the recent literature (2018-2021) indicates that successful HIE improves healthcare delivery, often resulting in improved health outcomes. There remain major opportunities for expanded use of HIE, including the active engagement of clinical and patient stakeholders. The maturity of HIE reflects the maturity of the biomedical informatics and health data science fields.



Publication History

Article published online:
04 December 2022

© 2022. IMIA and Thieme. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 McDonald CJ. The barriers to electronic medical record systems and how to overcome them. J Am Med Inform Assoc 1997 May-Jun;4(3):213-21.
  • 2 Weed LL. Medical records that guide and teach. N Engl J Med 1968 Mar 14;278(11):593-600.
  • 3 Adler-Milstein J, Ronchi E, Cohen GR, Winn LA, Jha AK. Benchmarking health IT among OECD countries: better data for better policy. J Am Med Inform Assoc 2014 Jan-Feb;21(1):111-6.
  • 4 Zelmer J, Ronchi E, Hyppönen H, Lupiáñez-Villanueva F, Codagnone C, Nøhr C, et al. International health IT benchmarking: learning from cross-country comparisons. J Am Med Inform Assoc 2017 Mar 1;24(2):371-9..
  • 5 Verma N, Mamlin B, Flowers J, Acharya S, Labrique A, Cullen T. OpenMRS as a global good: Impact, opportunities, challenges, and lessons learned from fifteen years of implementation. Int J Med Inform 2021 May;149:104405.
  • 6 HIMSS. Interoperability in Healthcare: HIMSS. Available from: https://www.himss.org/resources/interoperability-healthcare
  • 7 Oemig F, Snelick R. Healthcare Interoperability Standards Compliance Handbook: Conformance and Testing of Healthcare Data Exchange Standards. Cham: Springer International Publishing; 2016.
  • 8 NLM. MeSH Descriptor Data 2022: Health Information Exchange. Available from: https://meshb.nlm.nih.gov/record/ui?ui=D066275
  • 9 Akhlaq A, McKinstry B, Muhammad KB, Sheikh A. Barriers and facilitators to health information exchange in low- and middle-income country settings: a systematic review. Health Policy Plan 2016 Nov;31(9):1310-25.
  • 10 Bloomrosen M, Berner ES. Findings from the 2017 Yearbook Section on Health Information Management. Yearb Med Inform 2017 Aug;26(1):78-83.
  • 11 Bloomrosen M, Berner ES; Section Editors for the IMIA Yearbook Section on Health Information Management. Findings from 2017 on Health Information Management. Yearb Med Inform 2018 Aug;27(1):67-73.
  • 12 Bloomrosen M, Berner ES; Section Editors for the IMIA Yearbook Section on Health Information Management. Findings from the 2021 Yearbook Section on Health Information Management. Yearb Med Inform 2021 Aug;30(1):84-90.
  • 13 Bougioukas KI, Bouras EC, Avgerinos KI, Dardavessis T, Haidich AB. How to keep up to date with medical information using web-based resources: a systematised review and narrative synthesis. Health Info Libr J 2020 Dec;37(4):254-92.
  • 14 Cheung A, van Velden FH, Lagerburg V, Minderman N. The organizational and clinical impact of integrating bedside equipment to an information system: a systematic literature review of patient data management systems (PDMS). Int J Med Inform 2015 Mar;84(3):155-65.
  • 15 Eden KB, Totten AM, Kassakian SZ, Gorman PN, McDonagh MS, Devine B, et al. Barriers and facilitators to exchanging health information: a systematic review. Int J Med Inform 2016 Apr;88:44-51.
  • 16 Garza M, Myneni S, Nordo A, Eisenstein EL, Hammond WE, Walden A, et al. eSource for Standardized Health Information Exchange in Clinical Research: A Systematic Review. Stud Health Technol Inform 2019;257:115-24.
  • 17 Goss KD, Ioerger M, Young V, Flanders RM, Turk MA. A systematic search and technical review of online information pertaining to medical care for people with disability. Disabil Health J 2020 Apr;13(2):100877.
  • 18 Howe N, Giles E, Newbury-Birch D, McColl E. Systematic review of participants’ attitudes towards data sharing: a thematic synthesis. J Health Serv Res Policy 2018 Apr;23(2):123-33.
  • 19 Hurst D, Mickan S. Describing knowledge encounters in healthcare: a mixed studies systematic review and development of a classification. Implement Sci 2017 Mar 14;12(1):35.
  • 20 Jayabalan M, O’Daniel T. Access control and privilege management in electronic health record: a systematic literature review. J Med Syst 2016 Dec;40(12):261.
  • 21 Kash BA, Baek J, Davis E, Champagne-Langabeer T, Langabeer JR 2nd. Review of successful hospital readmission reduction strategies and the role of health information exchange. Int J Med Inform 2017 Aug;104:97-104.
  • 22 Kruse CS, Marquez G, Nelson D, Palomares O. The Use of Health Information Exchange to Augment Patient Handoff in Long-Term Care: A Systematic Review. Appl Clin Inform 2018 Oct;9(4):752-71.
  • 23 Leniz J, Weil A, Higginson IJ, Sleeman KE. Electronic palliative care coordination systems (EPaCCS): a systematic review. BMJ Support Palliat Care 2020 Mar;10(1):68-78.
  • 24 Mayer AH, da Costa CA, Righi RDR. Electronic health records in a Blockchain: A systematic review. Health Informatics J 2020 Jun;26(2):1273-88.
  • 25 Menachemi N, Rahurkar S, Harle CA, Vest JR. The benefits of health information exchange: an updated systematic review. J Am Med Inform Assoc 2018 Sep 1;25(9):1259-65.
  • 26 O’Donoghue O, Vazirani AA, Brindley D, Meinert E. Design Choices and Trade-Offs in Health Care Blockchain Implementations: Systematic Review. J Med Internet Res 2019 May 10;21(5):e12426.
  • 27 Ovies-Bernal DP, Agudelo-Londòno SM. Lecciones aprendidas en la implementaciòn de sistemas nacionales de informaciòn de salud interoperables: una revisiòn sistemática [Lessons learned in the implementation of interoperable National Health Information Systems: a systematic review]. Rev Panam Salud Publica 2014 May-Jun;35(5-6):415-23. Spanish.
  • 28 Prihodova L, Guerin S, Tunney C, Kernohan WG. Key components of knowledge transfer and exchange in health services research: Findings from a systematic scoping review. J Adv Nurs 2019 Feb;75(2):313-26.
  • 29 Rudin RS, Motala A, Goldzweig CL, Shekelle PG. Usage and effect of health information exchange: a systematic review. Ann Intern Med 2014 Dec 2;161(11):803-11.
  • 30 Sadoughi F, Nasiri S, Ahmadi H. The impact of health information exchange on healthcare quality and cost-effectiveness: A systematic literature review. Comput Methods Programs Biomed 2018 Jul;161:209-32.
  • 31 Sbaffi L, Rowley J. Trust and Credibility in Web-Based Health Information: A Review and Agenda for Future Research. J Med Internet Res 2017 Jun 19;19(6):e218.
  • 32 Shen N, Bernier T, Sequeira L, Strauss J, Silver MP, Carter-Langford A, et al. Understanding the patient privacy perspective on health information exchange: A systematic review. Int J Med Inform 2019 May;125:1-12.
  • 33 Swain MJ, Kharrazi H. Feasibility of 30-day hospital readmission prediction modeling based on health information exchange data. Int J Med Inform 2015 Dec;84(12):1048-56.
  • 34 van der Meij E, Anema JR, Otten RH, Huirne JA, Schaafsma FG. The Effect of Perioperative E-Health Interventions on the Postoperative Course: A Systematic Review of Randomised and Non-Randomised Controlled Trials. PLoS One 2016 Jul 6;11(7):e0158612.
  • 35 Julia Programming Language 2022 Available from: https://julialang.org
  • 36 Health Information Technology for Economic and Clinical Health Act (HITECH Act) 2009. Available from: https://www.healthit.gov/sites/default/files/hitech_act_excerpt_from_arra_with_index.pdf
  • 37 21st Century Cures Act 2016. Available from: https://www.congress.gov/114/plaws/publ255/PLAW-114publ255.pdf
  • 38 NLM. MeSH Descriptor Data 2022: Information Dissemination. Available from: https://meshb.nlm.nih.gov/record/ui?ui=D033181
  • 39 Adler-Milstein J, Garg A, Zhao W, Patel V. A Survey Of Health Information Exchange Organizations In Advance Of A Nationwide Connectivity Framework. Health Aff (Millwood) 2021 May;40(5):736-44.
  • 40 Lin SC, Everson J, Adler-Milstein J. Technology, Incentives, or Both? Factors Related to Level of Hospital Health Information Exchange. Health Serv Res 2018 Oct;53(5):3285-308.
  • 41 Everson J, Patel V, Adler-Milstein J. Information blocking remains prevalent at the start of 21st Century Cures Act: results from a survey of health information exchange organizations. J Am Med Inform Assoc 2021 Mar 18;28(4):727-32.
  • 42 Hess CT. The Free Exchange of Health Information: Preventing Information Blocking. Adv Skin Wound Care 2018 Aug;31(8):383-4.
  • 43 Fredriksen E, Martinez S, Moe CE, Thygesen E. Communication and information exchange between primary healthcare employees and volunteers - Challenges, needs and possibilities for technology support. Health Soc Care Community 2020 Jul;28(4):1252-60.
  • 44 Klapman S, Sher E, Adler-Milstein J. A snapshot of health information exchange across five nations: an investigation of frontline clinician experiences in emergency care. J Am Med Inform Assoc 2018 Jun 1;25(6):686-93. Erratum in: J Am Med Inform Assoc 2018 Sep 1;25(9):1269.
  • 45 Chen M, Guo S, Tan X. Does Health Information Exchange Improve Patient Outcomes? Empirical Evidence From Florida Hospitals. Health Aff (Millwood) 2019 Feb;38(2):197-204.
  • 46 D’Amore JD, McCrary LK, Denson J, Li C, Vitale CJ, Tokachichu P, et al. Clinical data sharing improves quality measurement and patient safety. J Am Med Inform Assoc 2021 Jul 14;28(7):1534-42.
  • 47 Davoody N, Koch S, Krakau I, Hägglund M. Accessing and sharing health information for post-discharge stroke care through a national health information exchange platform - a case study. BMC Med Inform Decis Mak 2019 May 3;19(1):95.
  • 48 Guerrazzi Young C, Feldman SS, Hernandez SR. Inter-organizational information sharing and bundled payment reimbursement: Do hospitals in the US use health information exchange to collaborate? Int J Med Inform 2021 Jan;145:104298.
  • 49 Thew S, Leeming G, Ainsworth J. Addressing the Socio-Technical Challenges of Health Information Exchange Adoption: DataWell in Greater Manchester. Stud Health Technol Inform 2018;247:790-4.
  • 50 Watkinson F, Dharmayat KI, Mastellos N. A mixed-method service evaluation of health information exchange in England: technology acceptance and barriers and facilitators to adoption. BMC Health Serv Res 2021 Jul 25;21(1):737.
  • 51 Goodstein RS. Practitioner Application: How Does Electronic Health Information Exchange Affect Hospital Performance Efficiency? The Effects of Breadth and Depth of Information Sharing. J Healthc Manag 2018 May-Jun;63(3):228-9.
  • 52 Vest JR, Unruh MA, Shapiro JS, Casalino LP. The associations between query-based and directed health information exchange with potentially avoidable use of health care services. Health Serv Res 2019 Oct;54(5):981-93.
  • 53 Cho NE, Ke W, Atems B, Chang J. How Does Electronic Health Information Exchange Affect Hospital Performance Efficiency? The Effects of Breadth and Depth of Information Sharing. J Healthc Manag 2018 May-Jun;63(3):212-28.
  • 54 Everson J, Adler-Milstein J. Sharing information electronically with other hospitals is associated with increased sharing of patients. Health Serv Res. 2020 Feb;55(1):128-35.
  • 55 Gan D, Shen J, Xu M. Adaptive Learning Emotion Identification Method of Short Texts for Online Medical Knowledge Sharing Community. Comput Intell Neurosci 2019 Jun 25;2019:1604392.
  • 56 Hamdan AA, Shaqman M, Abu Karaky A, Hassona Y, Bouchard P. Medical reliability of a video-sharing website: The gingival recession model. Eur J Dent Educ 2019 May;23(2):175-83.
  • 57 Thapa P, Thapa A, Khadka N, Bhattarai R, Jha S, Khanal A, et al. YouTube lens to attention deficit hyperactivity disorder: a social media analysis. BMC Res Notes 2018 Dec 4;11(1):854.
  • 58 Hernandez MY, Hernandez M, Lopez DH, Gamez D, Lopez SR. What do health providers and patients tweet about schizophrenia? Early Interv Psychiatry 2020 Oct;14(5):613-8.
  • 59 Séroussi B, Bouaud J. The (Re)-Relaunching of the DMP, the French Shared Medical Record: New Features to Improve Uptake and Use. Stud Health Technol Inform 2018;247:256-60.
  • 60 Esmaeilzadeh P. Patients’ Perceptions of Different Information Exchange Mechanisms: An Exploratory Study in the United States. Methods Inf Med 2020 Aug;59(4-05):162-78.
  • 61 Esmaeilzadeh P, Mirzaei T, Dharanikota S. The impact of data entry structures on perceptions of individuals with chronic mental disorders and physical diseases towards health information sharing. Int J Med Inform 2020 Sep;141:104157.
  • 62 Zhuang Y, Sheets L, Shae Z, Tsai JJP, Shyu CR. Applying Blockchain Technology for Health Information Exchange and Persistent Monitoring for Clinical Trials. AMIA Annu Symp Proc 2018 Dec 5;2018:1167-75.
  • 63 NLM. MeSH Descriptor Data 2022: Delivery of Health Care. Available from: https://meshb.nlm.nih.gov/record/ui?ui=D003695
  • 64 Addis S, Holland-Hart D, Edwards A, Neal RD, Wood F. Implementing Prudent Healthcare in the NHS in Wales; what are the barriers and enablers for clinicians? J Eval Clin Pract 2019 Feb;25(1):104-10.
  • 65 Guerrazzi C. An International Perspective on Health Information Exchange: Adoption in OECD Countries With Different Health Care System Configurations. Med Care Res Rev 2020 Aug;77(4):299-311.
  • 66 De Pietro C, Francetic I. E-health in Switzerland: The laborious adoption of the federal law on electronic health records (EHR) and health information exchange (HIE) networks. Health Policy 2018 Feb;122(2):69-74.
  • 67 Vest JR, Unruh MA, Freedman S, Simon K. Health systems’ use of enterprise health information exchange vs single electronic health record vendor environments and unplanned readmissions. J Am Med Inform Assoc 2019 Oct 1;26(10):989-98.
  • 68 Zhuang Y, Chen YW, Shae ZY, Shyu CR. Generalizable Layered Blockchain Architecture for Health Care Applications: Development, Case Studies, and Evaluation. J Med Internet Res 2020 Jul 27;22(7):e19029.
  • 69 Nahm ES, Schoenbaum A, Behm C, Rowen L. Health Information Exchange: Practical Overview and Implications for Nursing Practice. J Nurs Adm 2020 Nov;50(11):584-9.
  • 70 Pellegrin K, Chan F, Pagoria N, Jolson-Oakes S, Uyeno R, Levin A. A Statewide Medication Management System: Health Information Exchange to Support Drug Therapy Optimization by Pharmacists across the Continuum of Care. Appl Clin Inform 2018 Jan;9(1):1-10.
  • 71 Oyeyemi AO, Scott P. Interoperability in Health and Social Care: Organizational Issues are the Biggest Challenge. J Innov Health Inform 2018 Oct 31;25(3):196-8.
  • 72 Kasthurirathne SN, Biondich PG, Grannis SJ, Purkayastha S, Vest JR, Jones JF. Identification of Patients in Need of Advanced Care for Depression Using Data Extracted From a Statewide Health Information Exchange: A Machine Learning Approach. J Med Internet Res 2019 Jul 22;21(7):e13809.
  • 73 Mukhiya SK, Lamo Y. An HL7 FHIR and GraphQL approach for interoperability between heterogeneous Electronic Health Record systems. Health Informatics J 2021 Jul-Sep;27(3):14604582211043920.
  • 74 Thayer JG, Ferro DF, Miller JM, Karavite D, Grundmeier RW, Utidjian L, et al. Human-centered development of an electronic health record-embedded, interactive information visualization in the emergency department using fast healthcare interoperability resources. J Am Med Inform Assoc 2021 Jul 14;28(7):1401-10.
  • 75 Rucker DW. Implementing the Cures Act - Bringing Consumer Computing to Health Care. N Engl J Med 2020 May 7;382(19):1779-81.
  • 76 Lee K, Lim K, Jung SY, Ji H, Hong K, Hwang H, et al. Perspectives of Patients, Health Care Professionals, and Developers Toward Blockchain-Based Health Information Exchange: Qualitative Study. J Med Internet Res 2020 Nov 13;22(11):e18582.
  • 77 Kyburz P, Gfeller S, Bürkle T, Denecke K. Exchanging Appointment Data Among Healthcare Institutions. Stud Health Technol Inform 2019;260:33-40.
  • 78 Kiourtis A, Mavrogiorgou A, Menesidou SA, Gouvas P, Kyriazis D. A Secure Protocol for Managing and Sharing Personal Healthcare Data. Stud Health Technol Inform 2020 Nov 23;275:92-6.
  • 79 Esmaeilzadeh P, Mirzaei T, Maddah M. The effects of data entry structure on patients’ perceptions of information quality in Health Information Exchange (HIE). Int J Med Inform 2020 Mar;135:104058.
  • 80 Xiao D, Song C, Nakamura N, Nakayama M. Development of an application concerning fast healthcare interoperability resources based on standardized structured medical information exchange version 2 data. Comput Methods Programs Biomed 2021 Sep;208:106232.
  • 81 NLM. MeSH Descriptor Data 2022: Hospitals. Available from: https://meshb.nlm.nih.gov/record/ui?ui=D006761
  • 82 Walker DM. Does participation in health information exchange improve hospital efficiency? Health Care Manag Sci 2018 Sep;21(3):426-38.
  • 83 Lin SC, Hollingsworth JM, Adler-Milstein J. Alternative payment models and hospital engagement in health information exchange. Am J Manag Care 2019 Jan 1;25(1):e1-e6.
  • 84 Pylypchuk Y, Barker W, Encinosa W, Searcy T. Impact of the 2015 Health Information Technology Certification Edition on Interoperability among Hospitals. J Am Med Inform Assoc 2021 Aug 13;28(9):1866-73.
  • 85 Taura N, Matsumoto T, Honda M. The Evaluation of the Medical Information Exchange on 24-Hour Operation at North Kyushu Area in Japan. Stud Health Technol Inform 2019 Aug 21;264:1789-90.
  • 86 Chandrasekaran R, Sankaranarayanan B, Pendergrass J. Unfulfilled promises of health information exchange: What inhibits ambulatory clinics from electronically sharing health information? Int J Med Inform 2021 May;149:104418.
  • 87 Shields MC, Ritter G, Busch AB. Electronic Health Information Exchange At Discharge From Inpatient Psychiatric Care In Acute Care Hospitals. Health Aff (Millwood) 2020 Jun;39(6):958-67.
  • 88 Everson J, Adler-Milstein J. Gaps in health information exchange between hospitals that treat many shared patients. J Am Med Inform Assoc 2018 Sep 1;25(9):1114-21.
  • 89 Raymond L, Maillet Ë, Trudel MC, Marsan J, de Guinea AO, Paré G. Advancing laboratory medicine in hospitals through health information exchange: a survey of specialist physicians in Canada. BMC Med Inform Decis Mak 2020 Feb 28;20(1):44.
  • 90 Cho NE, Hong K, Chang J. Do Market Characteristics Matter? Factors Associated with Health Information Exchange. Int J Environ Res Public Health 2021 Nov 15;18(22):11976.
  • 91 Martinez DA, Feijoo F, Zayas-Castro JL, Levin S, Das TK. A strategic gaming model for health information exchange markets. Health Care Manag Sci 2018 Mar;21(1):119-30.
  • 92 Thoral PJ, Peppink JM, Driessen RH, Sijbrands EJG, Kompanje EJO, Kaplan L, et al; Amsterdam University Medical Centers Database (AmsterdamUMCdb) Collaborators and the SCCM/ESICM Joint Data Science Task Force. Sharing ICU Patient Data Responsibly Under the Society of Critical Care Medicine/European Society of Intensive Care Medicine Joint Data Science Collaboration: The Amsterdam University Medical Centers Database (AmsterdamUMCdb) Example. Crit Care Med 2021 Jun 1;49(6):e563-e577.
  • 93 Lakshmi Dhevi B, Vishvaksenan KS, Senthamil Selvan K, Rajalakshmi A. Patient Monitoring System Using Cognitive Internet of Things. J Med Syst 2018 Oct 11;42(11):229.
  • 94 Poirot E, Mills CW, Fair AD, Graham KA, Martinez E, Schreibstein L, et al. Evaluation of a health information exchange system for microcephaly case-finding - New York City, 2013-2015. PLoS One 2020 Aug 17;15(8):e0237392.
  • 95 Braund R, Lawrence CK, Baum L, Kessler B, Vassart M, Coulter C. Quality of electronic records documenting adverse drug reactions within a hospital setting: identification of discrepancies and information completeness. N Z Med J 2019 Jan 18;132(1488):28-37.
  • 96 Guerrazzi C, Feldman SS. Health information exchange: What matters at the organizational level? J Biomed Inform 2020 Feb;102:103375.
  • 97 Osheroff JA. Healthcare Information and Management Systems Society. Improving outcomes with clinical decision support : an implementer’s guide. 2nd ed. Chicago, IL: HIMSS; 2012.
  • 98 Centemero NS, Rechel B. Barriers and facilitators to a health information exchange system between general practitioners and hospitals: a qualitative study in Southern Switzerland. Swiss Med Wkly 2021 Oct 14;151:w30063.
  • 99 Rahurkar S, Vest JR, Finnell JT, Dixon BE. Trends in user-initiated health information exchange in the inpatient, outpatient, and emergency settings. J Am Med Inform Assoc 2021 Mar 1;28(3):622-7.
  • 100 Sarzynski E, Ensberg M, Parkinson A, Fitzpatrick L, Houdeshell L, Given C, et al. Eliciting nurses’ perspectives to improve health information exchange between hospital and home health care. Geriatr Nurs 2019 May-Jun;40(3):277-83.
  • 101 Woodward M, De Pennington N, Grandidge C, McCulloch P, Morgan L. Development and evaluation of an electronic hospital referral system: a human factors approach. Ergonomics 2020;63(6):710-23.
  • 102 NLM. MeSH Descriptor Data 2022: Emergency Service, Hospital. Available from: https://meshb.nlm.nih.gov/record/ui?ui=D004636
  • 103 Han X, Lowry TY, Loo GT, Rabin EJ, Grinspan ZM, Kern LM, et al. Expanding Health Information Exchange Improves Identification of Frequent Emergency Department Users. Ann Emerg Med 2019 Feb;73(2):172-9.
  • 104 Shy BD, Loo GT, Lowry T, Kim EY, Hwang U, Richardson LD, et al. Bouncing Back Elsewhere: Multilevel Analysis of Return Visits to the Same or a Different Hospital After Initial Emergency Department Presentation. Ann Emerg Med 2018 May;71(5):555-63.e1.
  • 105 Vest JR, Ben-Assuli O. Prediction of emergency department revisits using area-level social determinants of health measures and health information exchange information. Int J Med Inform 2019 Sep;129:205-10.
  • 106 Bell TM, Gilyan D, Moore BA, Martin J, Ogbemudia B, McLaughlin BE, et al. Long-term evaluation of a hospital-based violence intervention program using a regional health information exchange. J Trauma Acute Care Surg. 2018 Jan;84(1):175-82.
  • 107 Ben-Assuli O, Vest JR. Data mining techniques utilizing latent class models to evaluate emergency department revisits. J Biomed Inform 2020 Jan;101:103341.
  • 108 Dixon BE, Schwartzkopf AL, Guerrero VM, May J, Koufacos NS, Bean AM, et al. Regional data exchange to improve care for veterans after non-VA hospitalization: a randomized controlled trial. BMC Med Inform Decis Mak 2019 Jul 4;19(1):125.
  • 109 Gryczynski J, Nordeck CD, Martin RD, Welsh C, Schwartz RP, Mitchell SG, et al. Leveraging health information exchange for clinical research: Extreme underreporting of hospital service utilization among patients with substance use disorders. Drug Alcohol Depend 2020 Jul 1;212:107992.
  • 110 Rosenkrantz AB, Smith SW, Recht MP, Horwitz LI. Perceptions of Radiologists and Emergency Medicine Providers Regarding the Quality, Value, and Challenges of Outside Image Sharing in the Emergency Department Setting. AJR Am J Roentgenol 2020 Apr;214(4):843-52.
  • 111 Cummins MR, Del Fiol G, Crouch BI, Ranade-Kharkar P, Khalifa A, Iskander A, et al. Enabling health information exchange at a US Poison Control Center. J Am Med Inform Assoc 2020 Jul 1;27(7):1000-6.
  • 112 Schoenbaum AE, Seckman C. Impact of a Prescription Drug Monitoring Program on Health Information Exchange Utilization, Prescribing Behaviors, and Care Coordination in an Emergency Department. Comput Inform Nurs 2019 Dec;37(12):647-54.
  • 113 Vest JR, Unruh MA, Hilts KE, Sanner L, Jones J, Khokhar S, et al. End user information needs for a SMART on FHIR-based automated transfer form to support the care of nursing home patients during emergency department visits. AMIA Annu Symp Proc 2021 Jan 25;2020:1239-48.
  • 114 Koch S, Hersh WR, Bellazzi R, Leong TY, Yedaly M, Al-Shorbaji N. Digital Health during COVID-19: Informatics Dialogue with the World Health Organization. Yearb Med Inform 2021 Aug;30(1):13-6.
  • 115 Walker DM, Yeager VA, Lawrence J, McAlearney AS. Identifying Opportunities to Strengthen the Public Health Informatics Infrastructure: Exploring Hospitals’ Challenges with Data Exchange. Milbank Q 2021 Jun;99(2):393-425.
  • 116 Kasturi SN, Park J, Wild D, Khan B, Haggstrom DA, Grannis S. Predicting COVID-19-Related Health Care Resource Utilization Across a Statewide Patient Population: Model Development Study. J Med Internet Res 2021 Nov 15;23(11):e31337.
  • 117 Tortolero GA, Brown MR, Sharma SV, de Oliveira Otto MC, Yamal JM, Aguilar D, et al. Leveraging a health information exchange for analyses of COVID-19 outcomes including an example application using smoking history and mortality. PLoS One 2021 Jun 3;16(6):e0247235.
  • 118 Lenert L, McSwain BY. Balancing health privacy, health information exchange, and research in the context of the COVID-19 pandemic. J Am Med Inform Assoc 2020 Jun 1;27(6):963-6.
  • 119 O’Reilly-Shah VN, Gentry KR, Van Cleve W, Kendale SM, Jabaley CS, Long DR. The COVID-19 Pandemic Highlights Shortcomings in US Health Care Informatics Infrastructure: A Call to Action. Anesth Analg 2020 Aug;131(2):340-4.
  • 120 Newman N, Gilman S, Burdumy M, Yimen M, Lattouf O. A novel tool for patient data management in the ICU-Ensuring timely and accurate vital data exchange among ICU team members. Int J Med Inform 2020 Dec;144:104291.
  • 121 Murri R, Segala FV, Del Vecchio P, Cingolani A, Taddei E, Micheli G, et al; COVID II Columbus Group. Social media as a tool for scientific updating at the time of COVID pandemic: Results from a national survey in Italy. PLoS One 2020 Sep 3;15(9):e0238414.
  • 122 White-Dzuro CG, Schultz JD, Ye C, Coco JR, Myers JM, Shackelford C, et al. Extracting Medical Information from Paper COVID-19 Assessment Forms. Appl Clin Inform 2021 Jan;12(1):170-8.
  • 123 Wong SP, Jacobson HN, Massengill J, White HK, Yanamadala M. Safe Interorganizational Health Information Exchange During the COVID-19 Pandemic. J Am Med Dir Assoc 2020 Dec;21(12):1808-10.
  • 124 Elkefi S, Yu Z, Asan O. Online Medical Record Nonuse Among Patients: Data Analysis Study of the 2019 Health Information National Trends Survey. J Med Internet Res 2021 Feb 22;23(2):e24767.
  • 125 Ploner N, Neurath MF, Schoenthaler M, Zielke A, Prokosch HU. Concept to gain trust for a German personal health record system using public cloud and FHIR. J Biomed Inform 2019 Jul;95:103212.
  • 126 Phillips CA, Hunt A, Salvesen-Quinn M, Guerra J, Schapira MM, Bailey LC, et al. Health-related Google searches performed by parents of pediatric oncology patients. Pediatr Blood Cancer. 2019 Aug;66(8):e27795.
  • 127 Castaneda P, Sales A, Osborne NH, Corriere MA. Scope, Themes, and Medical Accuracy of eHealth Peripheral Artery Disease Community Forums. Ann Vasc Surg 2019 Jan;54:92-102.
  • 128 Cholowsky NL, Irvine JL, Simms JA, Pearson DD, Jacques WR, Peters CE, et al. The efficacy of public health information for encouraging radon gas awareness and testing varies by audience age, sex and profession. Sci Rep 2021 Jun 7;11(1):11906.
  • 129 Wallace R, Behringer B. Potential of technology to improve the availability and use of health information on cancer subjects for clergy from rural communities. Health Info Libr J 2020 Mar;37(1):35-47.
  • 130 Yeung T. Local health department adoption of electronic health records and health information exchanges and its impact on population health. Int J Med Inform 2019 Aug;128:1-6.
  • 131 Turvey CL, Klein DM, Nazi KM, Haidary ST, Bouhaddou O, Hsing N, et al. Racial differences in patient consent policy preferences for electronic health information exchange. J Am Med Inform Assoc 2020 May 1;27(5):717-25.
  • 132 Gill E, Dykes PC, Rudin RS, Storm M, McGrath K, Bates DW. Technology-facilitated care coordination in rural areas: What is needed? Int J Med Inform 2020 May;137:104102.
  • 133 NLM. MeSH Descriptor Data 2022: Computer Security. Available from: https://meshb.nlm.nih.gov/record/ui?ui=D016494
  • 134 NLM. MeSH Descriptor Data 2022: Confidentiality. Available from: https://meshb.nlm.nih.gov/record/ui?ui=D003219
  • 135 Ota S, Kudo KI, Taguchi K, Ihori M, Yoshie S, Yamamoto T, et al. Development of a gateway for interoperability in community-based care: An empirical study. Technol Health Care 2018;26(1):57-67.
  • 136 Tanaka K, Yamamoto R, Nakasho K, Miyaji A. Development of a Secure Cross-Institutional Data Collection System Based on Distributed Standardized EMR Storage. Stud Health Technol Inform 2018;255:35-9.
  • 137 Zheng Y, Lu R, Shao J. Achieving Efficient and Privacy-Preserving k-NN Query for Outsourced eHealthcare Data. J Med Syst 2019 Mar 27;43(5):123.
  • 138 De Backere F, Bonte P, Verstichel S, Ongenae F, De Turck F. Sharing health data in Belgium: A home care case study using the Vitalink platform. Inform Health Soc Care 2018 Jan;43(1):56-72.
  • 139 Trageser J, Davidson JE. Improving Speed and Security When Sharing Protected Health Information of Deceased Organ Donors. Prog Transplant 2019 Sep;29(3):279-82.
  • 140 Weiß JP, Welzel T, Hartmann BJ, Hübner U, Teuteberg F. Towards Designing a Secure Exchange Platform for Diabetes Monitoring and Therapy. Stud Health Technol Inform 2018;248:239-46.
  • 141 Esmaeilzadeh P. The Effects of Public Concern for Information Privacy on the Adoption of Health Information Exchanges (HIEs) by Healthcare Entities. Health Commun 2019 Sep;34(10):1202-11.
  • 142 Kisekka V, Giboney JS. The Effectiveness of Health Care Information Technologies: Evaluation of Trust, Security Beliefs, and Privacy as Determinants of Health Care Outcomes. J Med Internet Res 2018 Apr 11;20(4):e107.
  • 143 Amin R, Islam SH, Gope P, Choo KR, Tapas N. Anonymity Preserving and Lightweight Multimedical Server Authentication Protocol for Telecare Medical Information System. IEEE J Biomed Health Inform 2019 Jul;23(4):1749-59.
  • 144 Mandl KD, Kohane IS. Data Citizenship under the 21st Century Cures Act. N Engl J Med 2020 May 7;382(19):1781-3.
  • 145 Abdelhamid M. Greater patient health information control to improve the sustainability of health information exchanges. J Biomed Inform 2018 Jul;83:150-8.
  • 146 Kuziemsky CE, Gogia SB, Househ M, Petersen C, Basu A. Balancing Health Information Exchange and Privacy Governance from a Patient-Centred Connected Health and Telehealth Perspective. Yearb Med Inform 2018 Aug;27(1):48-54.
  • 147 Platt JE, Jacobson PD, Kardia SLR. Public Trust in Health Information Sharing: A Measure of System Trust. Health Serv Res 2018 Apr;53(2):824-45.
  • 148 Holen-Rabbersvik E, Thygesen E, Eikebrokk TR, Fensli RW, Slettebø Å. Barriers to exchanging healthcare information in inter-municipal healthcare services: a qualitative case study. BMC Med Inform Decis Mak 2018 Nov 7;18(1):92.
  • 149 Mello MM, Adler-Milstein J, Ding KL, Savage L. Legal Barriers to the Growth of Health Information Exchange-Boulders or Pebbles? Milbank Q 2018 Mar;96(1):110-43.
  • 150 Everson J, Butler E. Hospital adoption of multiple health information exchange approaches and information accessibility. J Am Med Inform Assoc 2020 Apr 1;27(4):577-83.
  • 151 Avci G, Esenkaya I. A legal overview of the use of messaging platforms in healthcare. Acta Orthop Traumatol Turc 2021 Jan;55(1):3-4.
  • 152 Mahmoud R, Moody AR, Foster M, Girdharry N, Sinn L, Zhang B, et al. Sharing De-identified Medical Images Electronically for Research: A Survey of Patients’ Opinion Regarding Data Management. Can Assoc Radiol J 2019 Aug;70(3):212-8.
  • 153 Renardi MB, Basjaruddin NC, Rakhman E. Securing electronic medical record in Near Field Communication using Advanced Encryption Standard (AES). Technol Health Care 2018;26(2):357-62.
  • 154 Dharminder D, Mishra D, Li X. Construction of RSA-Based Authentication Scheme in Authorized Access to Healthcare Services: Authorized Access to Healthcare Services. J Med Syst 2019 Nov 27;44(1):6.
  • 155 Qi M, Chen J, Chen Y. A secure biometrics-based authentication key exchange protocol for multi-server TMIS using ECC. Comput Methods Programs Biomed 2018 Oct;164:101-9.
  • 156 Renuka K, Kumari S, Li X. Design of a Secure Three-Factor Authentication Scheme for Smart Healthcare. J Med Syst 2019 Apr 3;43(5):133.
  • 157 Chen Y, Ding S, Xu Z, Zheng H, Yang S. Blockchain-Based Medical Records Secure Storage and Medical Service Framework. J Med Syst 2018 Nov 22;43(1):5.
  • 158 Esmaeilzadeh P, Mirzaei T. The Potential of Blockchain Technology for Health Information Exchange: Experimental Study From Patients’ Perspectives. J Med Internet Res 2019 Jun 20;21(6):e14184.
  • 159 Tian H, He J, Ding Y. Medical Data Management on Blockchain with Privacy. J Med Syst 2019 Jan 3;43(2):26.
  • 160 Zhuang Y, Sheets LR, Chen YW, Shae ZY, Tsai JJP, Shyu CR. A Patient-Centric Health Information Exchange Framework Using Blockchain Technology. IEEE J Biomed Health Inform 2020 Aug;24(8):2169-76.
  • 161 Tian YD, Menegay H, Waite KA, Saroufim PG, Beno MF, Barnholtz-Sloan JS. Facilitating Cancer Epidemiologic Efforts in Cleveland via Creation of Longitudinal De-Duplicated Patient Data Sets. Cancer Epidemiol Biomarkers Prev 2020 Apr;29(4):787-95.
  • 162 Ahmed W, Jagsi R, Gutheil TG, Katz MS. Public Disclosure on Social Media of Identifiable Patient Information by Health Professionals: Content Analysis of Twitter Data. J Med Internet Res 2020 Sep 1;22(9):e19746.
  • 163 Knight S, Hayhoe B, Papanikitas A, Sajid I. Ethical issues in the use of online social media forums by GPs. Br J Gen Pract 2019 Apr;69(681):203-4.
  • 164 Pevnick JM, Claver M, Dobalian A, Asch SM, Stutman HR, Tomines A, et al. Provider stakeholders’ perceived benefit from a nascent health information exchange: a qualitative analysis. J Med Syst 2012 Apr;36(2):601-13.
  • 165 Rudin R, Volk L, Simon S, Bates D. What Affects Clinicians’ Usage of Health Information Exchange? Appl Clin Inform 2011 Jan 1;2(3):250-62.
  • 166 Rudin RS. Why clinicians use or don’t use health information exchange. J Am Med Inform Assoc 2011 Jul-Aug;18(4):529.
  • 167 Shapiro JS. Evaluating public health uses of health information exchange. J Biomed Inform 2007 Dec;40(6 Suppl):S46-9.
  • 168 Vest JR, Zhao H, Jasperson J, Gamm LD, Ohsfeldt RL. Factors motivating and affecting health information exchange usage. J Am Med Inform Assoc 2011 Mar-Apr;18(2):143-9. Erratum in: J Am Med Inform Assoc 2011 May 1;18(3):348. Jaspserson, Jon [corrected to Jasperson, Jon].
  • 169 Holmgren AJ, Adler-Milstein J. Health Information Exchange in US Hospitals: The Current Landscape and a Path to Improved Information Sharing. J Hosp Med 2017 Mar;12(3):193-8.
  • 170 Vest JR, Kash BA. Differing Strategies to Meet Information-Sharing Needs: Publicly Supported Community Health Information Exchanges Versus Health Systems’ Enterprise Health Information Exchanges. Milbank Q 2016 Mar;94(1):77-108.
  • 171 Vest JR, Campion TR Jr, Kaushal R; HITEC Investigators. Challenges, alternatives, and paths to sustainability for health information exchange efforts. J Med Syst 2013 Dec;37(6):9987.
  • 172 Payne TH, Lovis C, Gutteridge C, Pagliari C, Natarajan S, Yong C, et al. Status of health information exchange: a comparison of six countries. J Glob Health 2019 Dec;9(2):0204279.
  • 173 Adler-Milstein J, Lin SC, Jha AK. The Number Of Health Information Exchange Efforts Is Declining, Leaving The Viability Of Broad Clinical Data Exchange Uncertain. Health Aff (Millwood) 2016 Jul 1;35(7):1278-85.
  • 174 Trusted Exchange Framework and Common Agreement (TEFCA) 2022. Available from: https://www.healthit.gov/topic/interoperability/trusted-exchange-framework-and-common-agreement-tefca
  • 175 Walker J, Pan E, Johnston D, Adler-Milstein J, Bates DW, Middleton B. The value of health care information exchange and interoperability. Health Aff (Millwood) 2005 Jan-Jun;Suppl Web Exclusives:W5-10-W5-18.
  • 176 Johnson KB, Unertl KM, Chen Q, Lorenzi NM, Nian H, Bailey J, et al. Health information exchange usage in emergency departments and clinics: the who, what, and why. J Am Med Inform Assoc 2011 Sep-Oct;18(5):690-7.
  • 177 Torres GW, Swietek K, Ubri PS, Singer RF, Lowell KH, Miller W. Building and strengthening infrastructure for data exchange: lessons from the beacon communities. EGEMS (Wash DC) 2014 Sep 25;2(3):1092.
  • 178 Zayas-Cabán T, Chaney KJ, Rogers CC, Denny JC, White PJ. Meeting the challenge: Health information technology’s essential role in achieving precision medicine. J Am Med Inform Assoc 2021 Jun 12;28(6):1345-52.
  • 179 Allen C, Des Jardins TR, Heider A, Lyman KA, McWilliams L, Rein AL, et al. Data governance and data sharing agreements for community-wide health information exchange: lessons from the beacon communities. EGEMS (Wash DC) 2014 Apr 23;2(1):1057.
  • 180 Williams C, Mostashari F, Mertz K, Hogin E, Atwal P. From the Office of the National Coordinator: the strategy for advancing the exchange of health information. Health Aff (Millwood) 2012 Mar;31(3):527-36. Erratum in: Health Aff (Millwood).2012 Mar;31(3):886.
  • 181 Jenkins ML. Health IT advances for the 21st century. J Am Assoc Nurse Pract 2021 May 18;34(2):405-9.
  • 182 Yasnoff WA, Humphreys BL, Overhage JM, Detmer DE, Brennan PF, Morris RW, et al. A consensus action agenda for achieving the national health information infrastructure. J Am Med Inform Assoc 2004 Jul-Aug;11(4):332-8.
  • 183 Vest JR, Gamm LD. Health information exchange: persistent challenges and new strategies. J Am Med Inform Assoc 2010 May-Jun;17(3):288-94.
  • 184 Deering MJ. Developing the health information infrastructure in the United States. Stud Health Technol Inform 2002;80:121-8.
  • 185 Devine EB, Totten AM, Gorman P, Eden KB, Kassakian S, Woods S, et al. Health Information Exchange Use (1990-2015): A Systematic Review. EGEMS (Wash DC) 2017 Dec 7;5(1):27.
  • 186 Kuperman GJ. Health-information exchange: why are we doing it, and what are we doing? J Am Med Inform Assoc 2011 Sep-Oct;18(5):678-82.
  • 187 Unertl KM, Johnson KB, Lorenzi NM. Health information exchange technology on the front lines of healthcare: workflow factors and patterns of use. J Am Med Inform Assoc 2012 May-Jun;19(3):392-400.
  • 188 Ash JS, Guappone KP. Qualitative evaluation of health information exchange efforts. J Biomed Inform 2007 Dec;40(6 Suppl):S33-9.
  • 189 Edwards A, Hollin I, Barry J, Kachnowski S. Barriers to cross--institutional health information exchange: a literature review. J Healthc Inf Manag 2010 Summer;24(3):22-34.
  • 190 Vest JR, Jasperson J. What should we measure? Conceptualizing usage in health information exchange. J Am Med Inform Assoc 2010 May-Jun;17(3):302-7.
  • 191 Hyppönen H, Reponen J, Lääveri T, Kaipio J. User experiences with different regional health information exchange systems in Finland. Int J Med Inform 2014 Jan;83(1):1-18.
  • 192 Akhlaq A, Sheikh A, Pagliari C. Health Information Exchange as a Complex and Adaptive Construct: Scoping Review. J Innov Health Inform 2017 Jan 25;23(4):889.