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CC BY-NC-ND 4.0 · Indian Journal of Neurosurgery 2023; 12(01): 086-089
DOI: 10.1055/s-0042-1742476
Short Communication

High-Grade Astroblastoma in a Young Female: An Enigma with a Rare Cautionary Tale

Mukta Meel 
1   Department of Pathology, SMS Medical College, Jaipur, Rajasthan, India
,
Ashok Gandhi
2   Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India
,
Arpita Jindal
1   Department of Pathology, SMS Medical College, Jaipur, Rajasthan, India
,
Mukesh Kumar
2   Department of Neurosurgery, SMS Medical College, Jaipur, Rajasthan, India
› Author Affiliations Funding None.
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Abstract

Astroblastoma is an uncommon neuroepithelial primary brain neoplasm with speculative histopathological origin and unpredictable clinical behavior. They can be easily misdiagnosed, as they are rarely encountered in clinical practice and share common radiological and histopathologic appearances with other glial neoplasms. Herein, we report a case of high-grade astroblastoma in a 27-year-old female with complaints of seizures and loss of consciousness, which was misdiagnosed as atypical meningioma on neuroimaging, due to its rarity and superficial cortical location appearing as extra-axial mass. Although intraoperative findings were also of an extra-axial tumor, the histology and immunophenotype was of an astroblastoma; thus, highlighting the role of histopathology and immunohistochemistry.

Keywords

astroblastoma - histology - neuroepithelial brain tumor


Publication History

Article published online:
26 April 2022

© 2021. Neurological Surgeons' Society of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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