SARS-CoV-2 Rapid Antigen Detection in Respiratory and Nonrespiratory Specimens in COVID-19 Patients

Vandana Vijayeta Kiro; Parul Singh; Sharad Srivastav; Richa Aggarwal; Kapil Dev Soni; Yudhyavir Singh; Abhishek Singh; Anjan Trikha; Purva Mathur

doi:10.1055/s-0042-1742415

Journal of Laboratory Physicians, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · J Lab Physicians 2022; 14(03): 369-372
DOI: 10.1055/s-0042-1742415

Brief Report

SARS-CoV-2 Rapid Antigen Detection in Respiratory and Nonrespiratory Specimens in COVID-19 Patients

Authors

Vandana Vijayeta Kiro

¹Department of Microbiology, Jai Prakash Narayan Apex Trauma Center (JPNATC), All India Institute of Medical Sciences, New Delhi, India
Parul Singh

¹Department of Microbiology, Jai Prakash Narayan Apex Trauma Center (JPNATC), All India Institute of Medical Sciences, New Delhi, India
Sharad Srivastav

²Junior Research Fellow Program, Jai Prakash Narayan Apex Trauma Center (JPNATC), All India Institute of Medical Sciences, New Delhi, India
Richa Aggarwal

³Department of Anaesthesia and Critical Care, All India Institute of Medical Sciences IIMS, New Delhi, India
Kapil Dev Soni

³Department of Anaesthesia and Critical Care, All India Institute of Medical Sciences IIMS, New Delhi, India
Yudhyavir Singh

³Department of Anaesthesia and Critical Care, All India Institute of Medical Sciences IIMS, New Delhi, India
Abhishek Singh

³Department of Anaesthesia and Critical Care, All India Institute of Medical Sciences IIMS, New Delhi, India
Anjan Trikha

³Department of Anaesthesia and Critical Care, All India Institute of Medical Sciences IIMS, New Delhi, India
Purva Mathur

⁴Division of Clinical Microbiology, Department of Laboratory Medicine, Jai Prakash Narayan Apex Trauma Center (JPNATC), All India Institute of Medical Sciences, New Delhi, India

Abstract

Rapid antigen testing for coronavirus disease 2019 (COVID-19) available at present provides immediate results at low cost with less expertise and without any need of sophisticated infrastructure. Most of these test kits available are for nasopharyngeal samples. This is a novel study to detect the presence of COVID antigen in samples other than throat and oropharyngeal. Various samples received from patients admitted in the COVID-19 dedicated center were tested for the presence of antigen. Same procedure was followed as done for the nasopharyngeal sample. A total of 150 samples were tested, which included ascitic fluid, pleural fluid, drain fluid, bile, bronchoalveolar lavage, cerebrospinal fluid, endotracheal tube aspirate, sputum, tissue, and urine. Out of 150, 11 (7.33%) were positive and 138 (92.66%) were negative for the antigen test. The COVID-19 antigen test kit, though designed for nasopharyngeal samples, was able to detect the presence of antigen in other clinical samples.

Keywords

COVID-19 - SARS-CoV-2 - rapid antigen test - nasopharyngeal - nonrespiratory samples

Volltext

Referenzen

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