Endoscopy 2017; 49(02): 176-180
DOI: 10.1055/s-0042-119267
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

A newly developed continuous zoom-focus endocytoscope

Youichi Kumagai
1   Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan
,
Kaiyo Takubo
2   Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
,
Kenro Kawada
3   Department of Esophageal and General Surgery, Tokyo Medical and Dental University, Tokyo, Japan
,
Morihiro Higashi
4   Department of Pathology, Saitama Medical Center, Saitama Medical University, Saitama, Japan
,
Toru Ishiguro
1   Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan
,
Jun Sobajima
1   Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan
,
Minoru Fukuchi
1   Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan
,
Kei-ichiro Ishibashi
1   Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan
,
Erito Mochiki
1   Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan
,
Junko Aida
2   Research Team for Geriatric Pathology, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan
,
Tatsuyuki Kawano
3   Department of Esophageal and General Surgery, Tokyo Medical and Dental University, Tokyo, Japan
,
Hideyuki Ishida
1   Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Saitama, Japan
› Author Affiliations
Further Information

Publication History

submitted17 May 2016

accepted after revision16 September 2016

Publication Date:
14 November 2016 (online)

Abstract

Background and study aims We report the features of a newly developed endocytoscopy system (ECS), the GIF-Y0074.

Patients and methods The GIF-Y0074 offers high-definition resolution with a consecutive increase of magnification to × 500. Using ECS, we observed 32 cases of esophageal squamous cell carcinoma (ESCC), 11 cases of gastric cancer, and five cases of duodenal adenoma.

Results The images of cells obtained using the GIF-Y0074 at maximum magnification were brighter and clearer than those obtained with previous ECS systems. For diagnosis of ESCC, clearer visualization of the nucleus made nuclear abnormality easier to recognize. Cancer cells were visualized in 10/11 cases of gastric cancer, but removal of mucus still remained a problem. Duodenal adenomas were found to have atypical cells with villi and tubules at the mucosal surface, thus assisting their histological diagnosis in vivo.

Conclusion The GIF-Y0074 is an excellent ECS in terms of ease of use, satisfactory resolution, and magnification power, and therefore achieves a level of utility that makes its commercial release justifiable. This ECS heralds a new era of endoscopic and histological diagnosis.