pferde spiegel 2016; 19(04): 174-175
DOI: 10.1055/s-0042-112434
labor
Enke Verlag in Georg Thieme Verlag KG Stuttgart · New York

Serum Amyloid A – ein Update

Antje Wöckener
Further Information

Publication History

Publication Date:
12 December 2016 (online)

Serum Amyloid A zählt zu den Akute-Phase-Proteinen und ist ein sensitiver Marker eines frühen Entzündungsgeschehens. Aufgrund seines raschen Anstiegs und seiner kurzen Halbwertszeit dient er einem zeitnahen Monitoring entzündlicher Prozesse. Gleichzeitig ist er ein stabiler Parameter und den herkömmlichen Entzündungsmarkern (Leukozyten, Fibrinogen etc.) in manchem Einsatzgebiet überlegen.

 
  • Literatur

  • 1 Andersen SA, Petersen HH, Ersvoll AK et al. Vaccination elicits a prominent acute phase response in horses. Vet J 2012; 191: 199-202
  • 2 Belgrave RL, Dickey MM, Arheart KL et al. Assessment of serum amyloid A testing of horses and its clinical application in a specialized equine practice. J Am Vet Med Assoc 2013; 1: 242
  • 3 Canisso IF, Ball BA, Cray C et al. Serum amyloid A and haptoglobin concentrations are increased in plasma of mares with ascending placentitis in the absence of changes in peripheral leukocyte counts or fibrinogen concentration. Am J Reprod Immunol 2014; 72: 376-385
  • 4 Cywinska A, Szarska E, Gorecka R et al. Acute phase protein concentrations after limited distance and long distance endurance rides in horses. Res Vet Sci 2012; 93: 1402-1406
  • 5 Hooijberg EH, van den Hoven R, Tichy A et al. Diagnostic and predictive capability of routine laboratory tests for the diagnosis and staging of equine inflammatory disease. J Vet Intern Med 2014; 28: 1587-1593
  • 6 Hulten C, Sandgren B, Skiöldebrand E et al. The acute phase protein serum amyloid A (SAA) as an inflammatory marker in equine influenza virus infection. Acta Vet Scand 1999; 40: 323-333
  • 7 Jacobsen S, Jensen JC, Frei S et al. Use of serum amyloid A and other acute phase reactants to monitor the inflammatory response after castration in horses. A field study. Equine Vet J 2005; 37: 552-556
  • 8 Jacobsen S, Niewold TA, Halling-Thomsen M et al. Serum amyloid A isoforms in serum and synovial fluid in horses with lipopolysaccharide-induced arthritis. Vet Immunol Immunopathol 2006; 110: 325-330
  • 9 Jacobsen S, Nielsen JV, Kjelgaard-Hansen M. Acute phase response to surgery of varying intensity in horses: a preliminary study. Vet Surg 2009; 38: 762-769
  • 10 Stoneham SJ, Palmer L, Cash R et al. Measurement of serum amyloid A in the neonatal foal using a latex agglutination immunoturbidimetric assay: determination of the normal range, variation with age and response to disease. Equine Vet J 2001; 33: 599-603
  • 11 Vandenplas ML, Moore JN, Barton MH et al. Concentrations of serum amyloid A and lipopolysaccharide-binding protein in horses with colic. Am J Vet Res 2005; 66: 1509-1516
  • 12 Westermann TL, Foster CM, Tornquist SJ et al. Evaluation of serum amyloid A and haptoglobin concentration as prognostic indicators for horses with colic. J Am Vet Med Assoc 2016; 248: 935-940