veterinär spiegel 2016; 26(03): 99-104
DOI: 10.1055/s-0042-111937
Kleintiere & Heimtiere
Zahnheilkunde
Enke Verlag in Georg Thieme Verlag KG Stuttgart · New York

Parodontitis – Mikroflora bei Hunden mit Parodontitis und Wirksamkeit von Antibiotika

Jacqueline Csokai
,
Sara Schirmer
,
Dorothee Geier-Dömling
,
Babette Klein
,
Gerhard Staudacher
,
Ines Ott
,
Elisabeth Müller
Further Information

Publication History

Publication Date:
09 September 2016 (online)

Parodontalerkrankungen sind ein häufiges Problem bei Hunden. Auf den Zähnen bildet sich innerhalb von 24 Stunden ein Zahnbelag (Plaque). Plaque ist prinzipiell ein Biofilm, bestehend aus zu Beginn vor allem grampositiven aeroben Bakterien (meist Streptococcus spp., Staphylococcus spp., Enterococcus spp.) in einer Matrix aus Glykoproteinen und Polysacchariden [16] . Bei Nichtentfernung der Plaque entwickelt sich eine Gingivitis und schließlich kommt es zur Parodontitis. Dabei nimmt die Anzahl der Bakterien stetig zu, wobei die gramnegativen Keime, einschließlich der Anaerobier, die Mehrheit darstellen [16], [17] . Die bei diesem Prozess entstehenden tiefen Zahntaschen stellen ein geeignetes Milieu zur Weitervermehrung der Bakterien dar, insbesondere der anaeroben Keime.

 
  • Literatur

  • 1 Al-Ali W, Bissada NF, Greenwell H. The effect of local doxycycline with and without tricalcium phosphate on the regenerative healing potential of periodontal osseous defects in dogs. J Periodontol 1989; 60: 582-590
  • 2 Allaker RP, de Rosayro R, Young KA, Hardie JM. Prevalence of Porphyromonas and Prevotella species in the dental plaque of dogs. Vet Rec 1997; 140: 147-148
  • 3 Baker PJ, Butler R, Wikesjo UME. Bacterial sampling by absorbent paper points. An in vitro study. J Periodontol 1991; 62: 142-146
  • 4 Cleland Jr. WP. Nonsurgical periodontal therapy. Clin Tech Small Anim Pract 2000; 15: 221-225
  • 5 Dennis M, Wilson T, Woodward T. Retention of antimicrobial activity after reconstitution of doxycycline gel. J Vet Dent 2012; 29: 84-87
  • 6 Eickholz P, Kim TS, Bürklin T et al. Non-surgical periodontal therapy with adjunctive topical doxycycline: a double-blind randomized controlled multicenter study. J Clin Periodontol 2002; 29: 108-117
  • 7 Gonçalves MO, Coutinho-Filho WP, Pimenta FP et al. Periodontal disease as reservoir for multi-resistant and hydrolytic enterobacterial species. Letters in applied microbiology 2007; 44: 488-494
  • 8 Griffen AL, Becker MR, Lyons SR et al. Prevalence of Porphyromonas gingivalis and Periodontal Health Status. J Clin Microbiol 1998; 36: 3239-3242
  • 9 Hartroth B, Seyfahrt I, Conrads G. Sampling of periodontal pathogens by paper points: evaluation of basic parameters. Oral Microbiol Immunol 1999; 14: 326-333
  • 10 Harvey CE, Thornsberry C, Miller BR. Subgingival bacteria-comparison of culture results in dogs and cats with gingivitis. J Vet Dent 1995; 12: 147-150
  • 11 Harvey CE, Thornsberry C, Miller BR. Antimicrobial susceptibility of subgingival bacterial flora in dogs with gingivitis. J Vet Dent 1995; 12: 151-155
  • 12 Harvey CE. Use of Antibiotics in Management of Patients with Oral Diseases. 20th FECAVA Eurocongress 2014, Munich, Proceedings Saturday: 112 – 116.
  • 13 Jervøe-Storm PM, AlAhdab H, Koltzscher M et al. Comparison of curette and paper point sampling of subgingival plaque bacteria as analysed by real-time polymerase chain reaction. J Periodontol 2007; 78: 909-917
  • 14 Moreira CA, De Oliveira LC, Mendes MS et al. Biofilm production by clinical staphylococci strains from canine otitis. Braz J Microbiol 2012; 371-374
  • 15 Nielsen JP, Bisgaard M, Pedersen KB. Production of toxin in strains previously classified as Pasteurella multocida. Acta Pathol Microbiol Immunol Scand B 1986; 94: 203-204
  • 16 Niemiec BA. Periodontal disease pathogenisis, local and systemic effects. 61. Jahreskongress der DVG-Fachgruppe Deutsche Gesellschaft für Kleintiermedizin 2015, Berlin, Proceedings Sunday: 220 – 225.
  • 17 Pieri FA, Falci AP, Bourguignon E et al. Periodontal Disease in Dogs. In: Perez-Marin CC, (ed.) A Birdʼs-Eye View of Veterinary Medicine. Croctia: In Tech; 2012: 119-136 http://www.intechope.com
  • 18 Radice M, Martino PA, Reiter AM. Evaluation of subgingival bacteria in the dog and susceptibility to commonly used antibiotics. J Vet Dent 2006; 23: 219-224
  • 19 Ratka-Krüger P, Schacher B, Bürklin T et al. Non-surgical periodontal therapy with adjunctive topical doxycycline: a double-masked, randomized, controlled multicenter study. II. Microbiological results. J Periodontol 2005; 76: 66-74
  • 20 Senhorinho GN, Nakano V, Liu C et al. Occurrence and antimicrobial susceptibility of Porphyromonas spp. and Fusobacterium spp. in dogs with and without periodontitis. Anaerobe 2012; 18: 381-385
  • 21 Standar K. In vitro Modelle oraler Biofilme [Diss]. Universität Rostock; 2010
  • 22 Stephan B, Greife HA, Pridmore A et al. Activity of Pradofloxacin against Porphyromonas and Prevotella spp. Implicated in Periodontal Disease in Dogs: Susceptibility Test Data from a European Multicenter Study. Antimicrob Agents Chemother 2008; 52: 2149-2155
  • 23 Zetner K, Rothmüller G. Behandlung von Zahnfleischtaschen mit dem neuen Periozeutikum Doxirobe®. Prakt Tierarzt 2002; 3: 214-225