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Planta Med 2016; 82(15): 1351-1358
DOI: 10.1055/s-0042-110180
Biological and Pharmacological Activity
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

In Vitro Dermo-Cosmetic Evaluation of Bark Extracts from Common Temperate Trees

Jane Hubert
1   Institut de Chimie Moléculaire de Reims, UMR CNRS 7312, SFR CAPʼSANTE, UFR de Pharmacie, Université de Reims Champagne-Ardenne, Reims, France
,
Apostolis Angelis
1   Institut de Chimie Moléculaire de Reims, UMR CNRS 7312, SFR CAPʼSANTE, UFR de Pharmacie, Université de Reims Champagne-Ardenne, Reims, France
2   Division of Pharmacognosy and Natural Products Chemistry, School of Pharmacy, University of Athens, Panepistimioupolis, Zographou, Athens, Greece
,
Nektarios Aligiannis
2   Division of Pharmacognosy and Natural Products Chemistry, School of Pharmacy, University of Athens, Panepistimioupolis, Zographou, Athens, Greece
,
Michalea Rosalia
2   Division of Pharmacognosy and Natural Products Chemistry, School of Pharmacy, University of Athens, Panepistimioupolis, Zographou, Athens, Greece
,
Amin Abedini
1   Institut de Chimie Moléculaire de Reims, UMR CNRS 7312, SFR CAPʼSANTE, UFR de Pharmacie, Université de Reims Champagne-Ardenne, Reims, France
3   Biomatériaux et Inflammation en Site Osseux, EA 4691, SFR CAP-Santé, UFR de Pharmacie, Université de Reims Champagne Ardenne, Reims, France
,
Ali Bakiri
1   Institut de Chimie Moléculaire de Reims, UMR CNRS 7312, SFR CAPʼSANTE, UFR de Pharmacie, Université de Reims Champagne-Ardenne, Reims, France
4   Soliance-Givaudan, Pomacle, France
,
Romain Reynaud
4   Soliance-Givaudan, Pomacle, France
,
Jean-Marc Nuzillard
1   Institut de Chimie Moléculaire de Reims, UMR CNRS 7312, SFR CAPʼSANTE, UFR de Pharmacie, Université de Reims Champagne-Ardenne, Reims, France
,
Sophie C. Gangloff
3   Biomatériaux et Inflammation en Site Osseux, EA 4691, SFR CAP-Santé, UFR de Pharmacie, Université de Reims Champagne Ardenne, Reims, France
,
Alexios-Leandros Skaltsounis
2   Division of Pharmacognosy and Natural Products Chemistry, School of Pharmacy, University of Athens, Panepistimioupolis, Zographou, Athens, Greece
,
Jean-Hugues Renault
1   Institut de Chimie Moléculaire de Reims, UMR CNRS 7312, SFR CAPʼSANTE, UFR de Pharmacie, Université de Reims Champagne-Ardenne, Reims, France
› Author Affiliations
Further Information

Publication History

received 29 February 2016
revised 23 May 2016

accepted 01 June 2016

Publication Date:
28 June 2016 (online)

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Abstract

Wood residues produced from forestry activities represent an interesting source of biologically active, high value-added secondary metabolites. In this study, 30 extracts from 10 barks of deciduous and coniferous tree species were investigated for their potential dermo-cosmetic use. The extracts were obtained from Fagus sylvatica, Quercus robur, Alnus glutinosa, Prunus avium, Acer pseudoplatanus, Fraxinus excelsior, Populus robusta, Larix decidua, Picea abies, and Populus tremula after three successive solid/liquid extractions of the barks with n-heptane, methanol, and methanol/water. All extracts were evaluated for their radical scavenging capacity, for their elastase, collagenase, and tyrosinase inhibitory activities, as well as for their antibacterial activity against gram-positive Staphylococcus aureus. In parallel, the global metabolite profiles of all extracts were established by 1D and 2D NMR and related to their biological activity. The results showed that the methanol extracts of Q. robur, A. glutinosa, L. decidua, and P. abies barks exhibit particularly high activities on most bioassays, suggesting their promising use as active ingredients in the dermo-cosmetic industry.

Key words

barks - natural products - dermo-cosmetics - DPPH - Collagenase - elastas - tyrosinase - Staphylococcus aureus - nuclear magnetic resonance spectroscopy
 

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