NOTARZT 2016; 32(01): 12-13
DOI: 10.1055/s-0042-100776
Pro & Contra
© Georg Thieme Verlag KG Stuttgart · New York

Pro

Nasale Gabe von Naloxon im Rettungsdienst
Michael S. Dittmar
Further Information

Publication History

Publication Date:
26 February 2016 (online)

Die nasale Verabreichung von Naloxon unter Verwendung eines geeigneten Zerstäubers ist eine nicht-invasive und zeitsparende Möglichkeit zur Therapie von lebensbedrohlichen Opiatintoxikationen. Zahlreiche Studien belegen die Wirksamkeit und Sicherheit der intranasalen Applikation.

 
  • Literatur

  • 1 McDermott C, Collins NC. Prehospital Medication Administration: A Randomised Study Comparing Intranasal and Intravenous Routes. Emerg Med Int 2012; 2012: 476161
  • 2 Kerr D, Kelly A, Dietze P et al. Randomized controlled trial comparing the effectiveness and safety of intranasal and intramuscular naloxone for the treatment of suspected heroin overdose. Addiction 2009; 104: 2067-2074
  • 3 Barton ED, Colwell CB, Wolfe T et al. Efficacy of intranasal naloxone as a needleless alternative for treatment of opioid overdose in the prehospital setting. J Emerg Med 2005; 29: 265-271
  • 4 Robertson TM, Hendey GW, Stroh G et al. Intranasal Naloxone Is a Viable Alternative to Intravenous Naloxone for Prehospital Narcotic Overdose. Prehosp Emerg Care 2009; 13: 512-515
  • 5 Merlin MA, Saybolt M, Kapitanyan R et al. Intranasal naloxone delivery is an alternative to intravenous naloxone for opioid overdoses. Am J Emerg Med 2010; 28: 296-303
  • 6 Weber JM, Tataris KL, Hoffman JD et al. Can Nebulized Naloxone Be Used Safely and Effectively by Emergency Medical Services for Suspected Opioid Overdose?. Prehosp Emerg Care 2012; 16: 289-292
  • 7 Kelly A, Kerr D, Dietze P et al. Randomised trial of intranasal versus intramuscular naloxone in prehospital treatment for suspected opioid overdose. Med J Aust 2005; 182: 24-27
  • 8 Belz D, Lieb J, Rea T et al. Naloxone Use in a Tiered-Response Emergency Medical Services System. Prehosp Emerg Care 2006; 10: 468-471
  • 9 Loimer N, Hofmann P, Chaudhry HR. Nasal Administration of Naloxone Is as Effective as the Intravenous Route in Opiate Addicts. Subst Use Misuse 1994; 29: 819-827
  • 10 Deanovic D, Weiss M. Intranasale Medikamentenapplikation im Rettungsdienst bei Kindern. Notfall Rettungsmed 2015; 18: 606-611
  • 11 ratiopharm GmbH. Fachinformation Naloxon-ratiopharm 0,4 mg/ml. 04/2014
  • 12 Teleflex Incorporated. LMA MAD nasal - Intranasaler Mukosaler Zerstäuber (Gebrauchsanweisung). 2013
  • 13 Dittmar M, Bigalke M, Schüttler J et al. Maßnahmen der Not- und Regelkompetenz. Notfall Rettungsmed 2014; 17: 233-242