CC BY-NC-ND 4.0 · Indian J Cardiovasc Dis Women WINCARS 2021; 06(04): 241-247
DOI: 10.1055/s-0041-1742210
Original Article

Sex-Based Difference in Clinical Presentation and Outcomes—A Single-Center Experience

Harini Anandan
1   Department of Cardiology, The Madras Medical Mission, Chennai, Tamil Nadu, India
,
Rashmi Maharajan
1   Department of Cardiology, The Madras Medical Mission, Chennai, Tamil Nadu, India
,
Shahina Begam
1   Department of Cardiology, The Madras Medical Mission, Chennai, Tamil Nadu, India
,
Suma M. Victor
1   Department of Cardiology, The Madras Medical Mission, Chennai, Tamil Nadu, India
› Author Affiliations

Abstract

Background and Aim The aim of this study was to compare the gender-based differences in baseline characteristics, clinical presentation, and outcomes among patients who underwent percutaneous coronary intervention (PCI) in our institute.

Methods This is a single-center, retrospective observational study. A total of 1,595 patients underwent PCI from a period of January 2019 to December 2019, in which 1,293 were males and 302 were females. Demographic characteristics, clinical and procedural details, and their in-hospital outcomes were all collected and analyzed.

Results Females presenting with symptoms were older than males (58 vs. 60.8 years, p < 0.001) and had higher body mass index (26.2 ± 6.7 vs. 27.2 ± 4, p < 0.001). Risk factors like diabetes mellitus (57.8 vs. 69.5%, p < 0.001) and systemic hypertension (50.2 vs. 65%, p < 0.001) were more common in females. Women were more likely to present with unstable angina (16.2 vs. 22.7%, p-0.009) and the rate of thrombolysis is low in women who presented with ST-elevation myocardial infarction (13.5 vs. 6.3%, p < 0.001). There was no significant difference in in-hospital mortality between both groups, but bleeding complications were higher in females (1.3 vs. 4%, p-0.006).

Conclusion Women who underwent PCI tend to be older and had higher rates of diabetes, hypertension, and obesity. Although mortality rates did not differ between groups, bleeding risk is higher in women.

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Financial Disclosure

None.




Publication History

Article published online:
15 February 2022

© 2022. Women in Cardiology and Related Sciences. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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