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CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2022; 26(04): e630-e635
DOI: 10.1055/s-0041-1741437
Original Research

Selective Neck Dissection for Node-Positive Oral Cavity Squamous Cell Carcinoma: A Retrospective Cohort Study

Syed Salman Hashmi 
1   ENT Department, Peterborough City Hospital, Northwest Anglia NHS Foundation Trust, Peterborough, England
,
Akbar Abbas 
2   Department of ENT, Aga Khan University Hospital, Karachi, Sindh, Pakistan
,
Amna Bukhari 
3   Department of ENT and Head and Neck Surgery, Patel Hospital, Karachi, Sindh, Pakistan
,
Javeria Saeed 
4   Department of Orthopedics, Aga Khan University Hospital, Karachi, Sindh, Pakistan
,
Ali Shafqat 
3   Department of ENT and Head and Neck Surgery, Patel Hospital, Karachi, Sindh, Pakistan
,
Atif Hafeez Siddique
5   Department of Otolaryngology, Dow University of Health Sciences, Karachi, Sindh, Pakistan
,
Ahmed Raheem Buksh 
6   Department of Pathology and Laboratory of Medicine, Aga Khan University Hospital, Karachi, Sindh, Pakistan
,
Ghulam Murtaza 
7   Department of General Surgery, Patel Hospital, Karachi, Sindh, Pakistan
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Abstract

Introduction Selective neck dissection in clinically node-negative neck is considered the standard of care for oral squamous cell carcinomas (SCCs). Controversy still prevails in node-positive disease regarding the extent of neck dissection. In our part of the world, comprehensive neck dissection is mostly considered to be the minimal optimal treatment for palpable neck disease.

Objective To compare regional control and disease-specific survival between clinically node-positive and node-negative patients undergoing selective neck dissection for oral SCC.

Methods This was a retrospective cohort study conducted in the department of ENT, Head and Neck surgery at a tertiary care hospital. All patients with biopsy-proven oral and lip SCC, with or without nodal disease, who underwent selective neck dissection between April 2006 and July 2015 were included in the study.

Results During the study period, 111 patients with oral SCC underwent selective neck dissection, of whom 71 (62%) were clinically node-negative and 40 (38%) patients had clinically positive nodes in the neck. The mean follow-up was 16.62 months (standard deviation [SD]: 17.03). The overall regional control rates were 95 versus 96% for clinical negative versus positive nodes, respectively (p = 0.589). The disease-specific survival was 84.5% in the node negative group versus 82.5% in the node-positive group (p = 0.703).

Conclusion Selective neck dissection in node-positive neck oral SCC has similar regional control rates when compared with node-negative neck SCC. The difference in disease-specific survival between the two groups is also not significant.

Keywords

carcinoma - squamous cell/surgery - mouth neoplasms/therapy - neck dissection/methods - neoplasm recurrence, local - survival rate


Publication History

Received: 01 June 2020

Accepted: 04 February 2021

Article published online:
22 February 2022

© 2022. Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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