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DOI: 10.1055/s-0041-1740831
Prediction Microvascular Invasion of Hepatocellular Carcinoma Based on Tumor Margin Enhancing Pattern in Multiphase CT Scan
Background: This study aimed to predict microvascular invasion of hepatocellular carcinoma based on tumor margin enhancement of the preoperative multiphase CT images.
Materials and Methods: A total of 53 patients with HCC underwent preoperative multiphases CT scan were included in this study. Tumor margin enhancing patterns were analyzed in late arterial, portovenous, and delay phases. The CT features including peritumoral enhancement, arterial rim enhancement, presence of daughter nodule, complete capsule enhancement in portovenous/delay phase, and incomplete capsule enhancement in portavenous/delay phase were reviewed and calculation for sensitivity and specificity. Univariate analysis and multivariate analysis were used to identify predictive features for microvascular invasion (MVI).
Results: In late arterial phase, peritumoral enhancement or presence of daughter nodule were not predictor for MVI. Incomplete capsule enhancement in portovenous and delay phases were good predictor for MVI with odds ratios of 29.25 and 33.09, respectively. The sensitivity and specificity for incomplete capsule enhancement in portovenous phase were 69.23 and 96.86%, respectively. The sensitivity and specificity for incomplete capsule enhancement in delay phase were 71.79 and 96.86%, respectively.
Conclusion: Incomplete capsule enhancement in portovenous phase or delay phase were good predictor for MVI.
Publication History
Article published online:
14 December 2021
© 2021. The Pan Arab Interventional Radiology Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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