CC BY-NC-ND 4.0 · Journal of Clinical Interventional Radiology ISVIR 2023; 07(02): 075-080
DOI: 10.1055/s-0041-1740568
Original Article

Endovascular Treatment of Acute Ischemic Stroke in Patients Younger than 18 Years

Sibasankar Dalai
1   Department of Interventional Neuroradiology, Medicover Hospitals, Visakhapatnam, Andhra Pradesh, India
Uday Limaye
2   Department of Neurointervention, Lilavati Hospital, Mumbai, Maharashtra, India
Satyarao Kolli
3   Department of Neurology, Medicover Hospitals, Visakhapatnam, Andhra Pradesh, India
Mohan V. Sumedha Maturu
3   Department of Neurology, Medicover Hospitals, Visakhapatnam, Andhra Pradesh, India
Randhi Venkata Narayana
4   Department of Neurology, Seven Hills Hospitals, Visakhapatnam, Andhra Pradesh, India
Rajesh Pati
3   Department of Neurology, Medicover Hospitals, Visakhapatnam, Andhra Pradesh, India
Suresh Kumar Korada
4   Department of Neurology, Seven Hills Hospitals, Visakhapatnam, Andhra Pradesh, India
Kuchelababu Vankineni
5   Department of Anaesthesiology and Critical Care, Seven Hills Hospitals, Visakhapatnam, Andhra Pradesh, India
Anantamakula Sameera
6   Department of Radiodiagnosis, Medicover Hospitals, Visakhapatnam, Andhra Pradesh, India
Aravind Varma Datla
7   Department of Internal Medicine, Medicover Hospitals, Visakhapatnam, Andhra Pradesh, India
› Author Affiliations


Purpose Rapid and effective revascularization is very important in the treatment of acute ischemic stroke (AIS). Endovascular treatment is a promising modality in the management of AIS in young patients.

Methods We evaluated the clinical and imaging records in 14 patients younger than 18 years presenting within 6 hours of AIS. They received endovascular therapy (ET) either by mechanical thrombectomy, thromboaspiration, or both (Solumbra) between July 2017 and June 2021. The National Institute of Health Stroke Scale (NIHSS) score was calculated on admission and before the discharge of all patients. The 90-day modified Rankin Scale (mRS) score on disability-free outcome was also evaluated.

Results The mean preprocedure NIHSS score was 10.78 ± 2.11 that improved to 4.5 ± 1.88 after the procedure. Thrombolysis in cerebral infarction (TICI) grade 2b and 3 blood flow could be established in 12 (85.72%) patients. One patient had TICI 2a flow and one patient had recurrent occlusion despite repeated recanalization (TICI grade 0). The disability-free outcome, mRS score at 90 days was 0 to 1 in 12 (85.72%) patients, mRS score 2 in one (7.14%) patient, and mRS score 3 in one patient (7.14%). We did not have any major complication related to the procedure.

Conclusion ET provides high rates of arterial recanalization and favorable disability-free outcomes in young patients with AIS.

Ethical Approval

All participating centers have obtained ethical approval for the studies.

Publication History

Article published online:
29 December 2021

© 2021. Indian Society of Vascular and Interventional Radiology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (

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