CC BY 4.0 · European J Pediatr Surg Rep. 2022; 10(01): e1-e5
DOI: 10.1055/s-0041-1740328
Case Report

Porous Ceramic Sternal Prosthesis Implantation in a 13-Year-Old Patient Presenting with Metastatic Ewing's Sarcoma

1   Department of Pediatric Surgery, Jeanne de Flandre Hospital, Lille, France
,
Dyuti Sharma
1   Department of Pediatric Surgery, Jeanne de Flandre Hospital, Lille, France
2   Université Lille 2 Droit et Santé Faculté de Médecine Henri Warembourg, Lille, Hauts-de-France, France
,
Damien Fron
1   Department of Pediatric Surgery, Jeanne de Flandre Hospital, Lille, France
,
Aurélie Mezel
1   Department of Pediatric Surgery, Jeanne de Flandre Hospital, Lille, France
,
Federico Canavese
1   Department of Pediatric Surgery, Jeanne de Flandre Hospital, Lille, France
2   Université Lille 2 Droit et Santé Faculté de Médecine Henri Warembourg, Lille, Hauts-de-France, France
,
Michel Bonnevalle
3   Department of Pediatric Surgery, Reference Center for Congenital and Malformative Esophageal Disorders, Jeanne de Flandre Children's Hospital, Lille University Faculty of Medicine, Lille, France
,
Eric Nectoux
1   Department of Pediatric Surgery, Jeanne de Flandre Hospital, Lille, France
2   Université Lille 2 Droit et Santé Faculté de Médecine Henri Warembourg, Lille, Hauts-de-France, France
› Author Affiliations
Funding None.

Abstract

Ewing's sarcoma is the second most frequent primary malignant bone tumor in adolescents and young adults. Locations on the thoracic wall represent up to 20% of primary and secondary locations. We present the case of a 13-year-old patient treated with the use of a radiolucency porous bioceramic prosthesis as a sternal replacement for a wide tumor resection in an oncologic context. Focal radiation therapy was not possible due to the high risk of severe myocardial injuries caused by the sternal location of the tumor. The sternum CERAMIL® (I.CERAM, Limoges, France), in porous alumina (Al2O3) has already been implanted into adults in sternal replacement during its invasion by a tumor or its infectious destruction. There were no complication concerning the surgery. The last follow-up at 2 years postoperatively reveals a satisfactory clinical situation with any functional thoracic complaint and nor any functional respiratory symptoms. The porous alumina sternal prosthesis offers a reliable alternative for sternal replacement indications for children in an oncologic context.



Publication History

Received: 09 May 2021

Accepted: 23 September 2021

Article published online:
15 January 2022

© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Balamuth NJ, Womer RB. Ewing's sarcoma. Lancet Oncol 2010; 11 (02) 184-192
  • 2 Damron TA, Ward WG, Stewart A. Osteosarcoma, chondrosarcoma, and Ewing's sarcoma: National Cancer Data Base Report. Clin Orthop Relat Res 2007; 459 (459) 40-47
  • 3 Lacour B, Guyot-Goubin A, Guissou S, Bellec S, Désandes E, Clavel J. Incidence of childhood cancer in France: National Children Cancer Registries, 2000-2004. Eur J Cancer Prev 2010; 19 (03) 173-181
  • 4 Bosma SE, Ayu O, Fiocco M, Gelderblom H, Dijkstra PDS. Prognostic factors for survival in Ewing sarcoma: a systematic review. Surg Oncol 2018; 27 (04) 603-610
  • 5 Saenz NC, Hass DJ, Meyers P. et al. Pediatric chest wall Ewing's sarcoma. J Pediatr Surg 2000; 35 (04) 550-555
  • 6 Baino F, Novajra G, Vitale-Brovarone C. Bioceramics and scaffolds: a winning combination for tissue engineering. Front Bioeng Biotechnol 2015; 3: 202
  • 7 Galbis Caravajal JM, Yeste Sánchez L, Fuster Diana CA, Guijarro Jorge R, Fernández Ortiz P, Deaville PJ. Sternal resection and reconstruction after malignant tumours. Clin Transl Oncol 2009; 11 (02) 91-95
  • 8 Kaláb M, Karkoška J, Kamínek M. et al. Reconstruction of massive post-sternotomy defects with allogeneic bone graft: four-year results and experience using the method. Interact Cardiovasc Thorac Surg 2016; 22 (03) 305-313
  • 9 Skoracki RJ, Chang DW. Reconstruction of the chestwall and thorax. J Surg Oncol 2006; 94 (06) 455-465
  • 10 Seder CW, Rocco G. Chest wall reconstruction after extended resection. J Thorac Dis 2016; 8 (Suppl. 11) S863-S871
  • 11 Sanna S, Brandolini J, Pardolesi A. et al. Materials and techniques in chest wall reconstruction: a review. J Vis Surg 2017; 3: 95
  • 12 Bertin F, Piccardo A, Denes E, Delepine G, Tricard J. Porous alumina ceramic sternum: a reliable option for sternal replacement. Ann Thorac Med 2018; 13 (04) 226-229
  • 13 Fouilloux V, Bertin F, Peltier E, Jouve JL. First sternal cleft repair using a porous alumina ceramic prosthesis in a 9-year-old child. European J Pediatr Surg Rep 2019; 7 (01) e20-e23
  • 14 Denes E, Barrière G, Poli E, Lévêque G. Commentary: bioceramics and scaffolds: a winning combination for tissue engineering. Front Bioeng Biotechnol 2017; 5 (02) 15
  • 15 Cotterill SJ, Ahrens S, Paulussen M. et al. Prognostic factors in Ewing's tumor of bone: analysis of 975 patients from the European Intergroup Cooperative Ewing's Sarcoma Study Group. J Clin Oncol 2000; 18 (17) 3108-3114
  • 16 Poli E, Ouk TS, Barrière G, Lévèque G, Sol V, Denes E. Does low hydroxyl group surface density explain less bacterial adhesion on porous alumina?. Orthop Traumatol Surg Res 2019; 105 (03) 473-477
  • 17 Slullitel PA, Buttaro MA, Greco G. et al. No lower bacterial adhesion for ceramics compared to other biomaterials: an in vitro analysis. Orthop Traumatol Surg Res 2018; 104 (04) 439-443