Clin Colon Rectal Surg 2022; 35(03): 237-243
DOI: 10.1055/s-0041-1740102
Review Article

Necrotizing Soft Tissue Infections of the Perineum

Bryan P. Kline
1   Department of Surgery, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania
Nimalan A. Jeganathan
2   Division of Colon and Rectal Surgery, Department of Surgery, The Pennsylvania State University, College of Medicine, Hershey, Pennsylvania
› Author Affiliations
Funding This work was supported by the Marshia and Peter Carlino Early Career Professorship at Penn State Hershey Medical Center.


Necrotizing soft tissue infections of the perineum are rapidly progressing infections associated with significant morbidity and mortality. Prompt diagnosis and management with early surgical debridement is necessary to improve survival from this deadly disease. Repeat debridements are not uncommon. Important adjuncts to surgery include broad-spectrum antibiotics and management in an intensive care unit, as patients frequently develop multisystem organ failure. Once the acute phase is managed, fecal diversion with either an ostomy or fecal management catheter can be considered to decrease soiling of the wound and facilitate healing. Long-term management requires meticulous wound care, often with the assistance of negative pressure wound therapy. Patients may ultimately require skin grafts or tissue flaps for soft tissue coverage following extensive surgical debridements.

Publication History

Article published online:
09 February 2022

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